NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis - Guo, Xinyue; Xu, Xinxin; Li, Tiantian; Yu, Qin; Wang, Jianzhang; Chen, Yichen; Ding, Shaojie; Zhu, Libo; Zou, Gen; Zhang, Xinmei (Frontiers in immunology, 2021)
Keywords: Animals; Cell Line; endometriosis; Endometriosis - immunology; Estradiol - pharmacology; estrogen; Estrogen Receptor alpha - genetics; Estrogens - pharmacology; Female; Humans; Immunology; Inflammasomes - antagonists & inhibitors; Inflammasomes - genetics; Inflammasomes - immunology; Interleukin-1beta - immunology; interleukin-1β; mast cells; Mast Cells - drug effects; Mast Cells - immunology; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors; NLR Family, Pyrin Domain-Containing 3 Protein - genetics; NLR Family, Pyrin Domain-Containing 3 Protein - immunology; NLRP3 inflammasome; Peritoneal Cavity - cytology; Signal Transduction - drug effects; Thiazolidines - pharmacology; Thiones - pharmacology; endometriosis; estrogen; NLRP3 inflammasome; mast cells; interleukin-1β