The impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual function in women who carry a BRCA mutation

• Published in: Gynecologic oncology Vol. 121; no. 1; pp. 163 - 168
• Main Authors: Finch, A., Metcalfe, K.A., Chiang, J.K., Elit, L., McLaughlin, J., Springate, C., Demsky, R., Murphy, J., Rosen, B., Narod, S.A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2011
• Subjects: Adult; Aged; BRCA1; BRCA2; Fallopian Tube Neoplasms - genetics; Fallopian Tube Neoplasms - prevention & control; Female; Genes, BRCA1; Genes, BRCA2; Genetic Predisposition to Disease; Germ-Line Mutation; Hematology, Oncology and Palliative Medicine; Hormone Replacement Therapy; Humans; Menopausal symptoms; Menopause; Middle Aged; Obstetrics and Gynecology; Ovarian Neoplasms - genetics; Ovarian Neoplasms - prevention & control; Ovariectomy; Patient Satisfaction; Quality of Life; Salpingo-oophorectomy; Salpingostomy; Sexual Dysfunction, Physiological - etiology; Sexual functioning; Surveys and Questionnaires; Salpingo-oophorectomy; BRCA1; Menopausal symptoms; BRCA2; Sexual functioning

Prophylactic salpingo-oophorectomy is recommended to women who carry a BRCA1 or BRCA2 mutation to reduce the risks of breast, ovarian and fallopian tube cancer. We measured the impact of prophylactic salpingo-oophorectomy on menopausal symptoms and sexual functioning in women with a BRCA mutation. W...