ZebRA: An overview of retinoic acid signaling during zebrafish development

• Published in: Biochimica et biophysica acta Vol. 1849; no. 2; pp. 73 - 83
• Main Authors: Samarut, Eric, Fraher, Daniel, Laudet, Vincent, Gibert, Yann
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2015
• Subjects: Animals; Body Patterning - drug effects; Body Patterning - genetics; Danio rerio; Embryo, Nonmammalian; Embryogenesis; Embryonic Development - drug effects; Embryonic Development - genetics; Freshwater; Gene Expression Regulation, Developmental - drug effects; Organogenesis; Organogenesis - drug effects; Organogenesis - genetics; RAR; Retinoic acid; Signal Transduction - drug effects; Signal Transduction - genetics; Tretinoin - pharmacology; Tretinoin - physiology; Zebrafish; Zebrafish - embryology; Zebrafish - genetics; Zebrafish; RAR; Embryogenesis; Retinoic acid; Organogenesis

Retinoic acid (RA), the main active vitamin A derivative, is crucial for embryo development, regulating cellular processes, embryo patterning and organogenesis. Many studies performed in mammalian or avian models have successfully undertaken the investigation of the role played by RA during embryoge...