Forecasting the elimination of active trachoma: An empirical model
Background Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when the program will attain the goal of the elimination of active trachoma, defined as prevalence of trachomatous inflammation-follic...
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Published in | PLoS neglected tropical diseases Vol. 16; no. 7; p. e0010563 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
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11.07.2022
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Abstract | Background Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when the program will attain the goal of the elimination of active trachoma, defined as prevalence of trachomatous inflammation-follicular in 1-9 year olds (TF.sub.1-9) <5%. Here we use program data to create an empirical model predicting the year of attaining global elimination of TF.sub.1-9. Methodology/Principal findings We calculated the mean number of years (95% CI) observed for an implementation unit (IU) to move from a baseline TF.sub.1-9 prevalence [greater than or equal to]5% to the elimination threshold, based on the region (Ethiopia vs. non-Ethiopia) and baseline prevalence category. Ethiopia IUs had significantly different rates of reaching the TF.sub.1-9 elimination threshold after a trachoma impact survey (TIS) compared to non-Ethiopia IUs across all baseline categories. We used those estimates to predict when remaining active trachoma-endemic IUs (TF.sub.1-9 [greater than or equal to]5%) would have their last round of mass drug administration (MDA) based on the mean number of years required and number of MDA rounds already completed. Our model predicts that elimination of TF.sub.1-9 will be achieved in 2028 in Ethiopia (95% CI: 2026-2033) and 2029 outside of Ethiopia (95% CI: 2023-2034), with some IUs in East Africa predicted to be the last requiring MDA globally. Conclusions/Significance Our empirical estimate is similar to those resulting from previous susceptible-infectious-susceptible (SIS) and mathematical models, suggesting that the forecast achievement of TF.sub.1-9 elimination is realistic with the caveat that although disease elimination progress can be predicted for most IUs, there is an important minority of IUs that is not declining or has not yet started trachoma elimination activities. These IUs represent an important barrier to the timely global elimination of active trachoma. |
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AbstractList | Background Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when the program will attain the goal of the elimination of active trachoma, defined as prevalence of trachomatous inflammation-follicular in 1-9 year olds (TF.sub.1-9) <5%. Here we use program data to create an empirical model predicting the year of attaining global elimination of TF.sub.1-9. Methodology/Principal findings We calculated the mean number of years (95% CI) observed for an implementation unit (IU) to move from a baseline TF.sub.1-9 prevalence [greater than or equal to]5% to the elimination threshold, based on the region (Ethiopia vs. non-Ethiopia) and baseline prevalence category. Ethiopia IUs had significantly different rates of reaching the TF.sub.1-9 elimination threshold after a trachoma impact survey (TIS) compared to non-Ethiopia IUs across all baseline categories. We used those estimates to predict when remaining active trachoma-endemic IUs (TF.sub.1-9 [greater than or equal to]5%) would have their last round of mass drug administration (MDA) based on the mean number of years required and number of MDA rounds already completed. Our model predicts that elimination of TF.sub.1-9 will be achieved in 2028 in Ethiopia (95% CI: 2026-2033) and 2029 outside of Ethiopia (95% CI: 2023-2034), with some IUs in East Africa predicted to be the last requiring MDA globally. Conclusions/Significance Our empirical estimate is similar to those resulting from previous susceptible-infectious-susceptible (SIS) and mathematical models, suggesting that the forecast achievement of TF.sub.1-9 elimination is realistic with the caveat that although disease elimination progress can be predicted for most IUs, there is an important minority of IUs that is not declining or has not yet started trachoma elimination activities. These IUs represent an important barrier to the timely global elimination of active trachoma. Background Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when the program will attain the goal of the elimination of active trachoma, defined as prevalence of trachomatous inflammation—follicular in 1–9 year olds (TF1–9) <5%. Here we use program data to create an empirical model predicting the year of attaining global elimination of TF1–9. Methodology/Principal findings We calculated the mean number of years (95% CI) observed for an implementation unit (IU) to move from a baseline TF1–9 prevalence ≥5% to the elimination threshold, based on the region (Ethiopia vs. non-Ethiopia) and baseline prevalence category. Ethiopia IUs had significantly different rates of reaching the TF1–9 elimination threshold after a trachoma impact survey (TIS) compared to non-Ethiopia IUs across all baseline categories. We used those estimates to predict when remaining active trachoma-endemic IUs (TF1–9 ≥5%) would have their last round of mass drug administration (MDA) based on the mean number of years required and number of MDA rounds already completed. Our model predicts that elimination of TF1–9 will be achieved in 2028 in Ethiopia (95% CI: 2026–2033) and 2029 outside of Ethiopia (95% CI: 2023–2034), with some IUs in East Africa predicted to be the last requiring MDA globally. Conclusions/Significance Our empirical estimate is similar to those resulting from previous susceptible-infectious-susceptible (SIS) and mathematical models, suggesting that the forecast achievement of TF1–9 elimination is realistic with the caveat that although disease elimination progress can be predicted for most IUs, there is an important minority of IUs that is not declining or has not yet started trachoma elimination activities. These IUs represent an important barrier to the timely global elimination of active trachoma. Mathematical and statistical models have been used to forecast the global decline of active trachoma prevalence as a result of interventions against the disease. Here we used trachoma program data to create an empirical model predicting the year of attaining global elimination. We analyzed over 20 years of trachoma implementation and survey data to calculate the mean number of rounds of mass drug administration required for implementation units to fall below the elimination threshold for active trachoma. We then compared these means against the number of rounds of mass drug administration previously undertaken for all areas still above the elimination threshold to produce a forecast of the last year of antibiotic distribution for each implementation unit. Our model predicts that elimination will be achieved in 2028 in Ethiopia (95% CI: 2026–2033) and 2029 outside of Ethiopia (95% CI: 2023–2034), with areas in East Africa predicted to be the last requiring mass drug administration globally. However, although disease-elimination progress can be predicted for most implementation units, there is an important minority of implementation units that is not declining or has not yet begun implementation. These areas represent an important barrier to the timely global elimination of active trachoma. Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when the program will attain the goal of the elimination of active trachoma, defined as prevalence of trachomatous inflammation-follicular in 1-9 year olds (TF.sub.1-9) <5%. Here we use program data to create an empirical model predicting the year of attaining global elimination of TF.sub.1-9. We calculated the mean number of years (95% CI) observed for an implementation unit (IU) to move from a baseline TF.sub.1-9 prevalence [greater than or equal to]5% to the elimination threshold, based on the region (Ethiopia vs. non-Ethiopia) and baseline prevalence category. Ethiopia IUs had significantly different rates of reaching the TF.sub.1-9 elimination threshold after a trachoma impact survey (TIS) compared to non-Ethiopia IUs across all baseline categories. We used those estimates to predict when remaining active trachoma-endemic IUs (TF.sub.1-9 [greater than or equal to]5%) would have their last round of mass drug administration (MDA) based on the mean number of years required and number of MDA rounds already completed. Our model predicts that elimination of TF.sub.1-9 will be achieved in 2028 in Ethiopia (95% CI: 2026-2033) and 2029 outside of Ethiopia (95% CI: 2023-2034), with some IUs in East Africa predicted to be the last requiring MDA globally. Our empirical estimate is similar to those resulting from previous susceptible-infectious-susceptible (SIS) and mathematical models, suggesting that the forecast achievement of TF.sub.1-9 elimination is realistic with the caveat that although disease elimination progress can be predicted for most IUs, there is an important minority of IUs that is not declining or has not yet started trachoma elimination activities. These IUs represent an important barrier to the timely global elimination of active trachoma. BackgroundGreat progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when the program will attain the goal of the elimination of active trachoma, defined as prevalence of trachomatous inflammation-follicular in 1-9 year olds (TF1-9) <5%. Here we use program data to create an empirical model predicting the year of attaining global elimination of TF1-9.Methodology/principal findingsWe calculated the mean number of years (95% CI) observed for an implementation unit (IU) to move from a baseline TF1-9 prevalence ≥5% to the elimination threshold, based on the region (Ethiopia vs. non-Ethiopia) and baseline prevalence category. Ethiopia IUs had significantly different rates of reaching the TF1-9 elimination threshold after a trachoma impact survey (TIS) compared to non-Ethiopia IUs across all baseline categories. We used those estimates to predict when remaining active trachoma-endemic IUs (TF1-9 ≥5%) would have their last round of mass drug administration (MDA) based on the mean number of years required and number of MDA rounds already completed. Our model predicts that elimination of TF1-9 will be achieved in 2028 in Ethiopia (95% CI: 2026-2033) and 2029 outside of Ethiopia (95% CI: 2023-2034), with some IUs in East Africa predicted to be the last requiring MDA globally.Conclusions/significanceOur empirical estimate is similar to those resulting from previous susceptible-infectious-susceptible (SIS) and mathematical models, suggesting that the forecast achievement of TF1-9 elimination is realistic with the caveat that although disease elimination progress can be predicted for most IUs, there is an important minority of IUs that is not declining or has not yet started trachoma elimination activities. These IUs represent an important barrier to the timely global elimination of active trachoma. Background Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when the program will attain the goal of the elimination of active trachoma, defined as prevalence of trachomatous inflammation—follicular in 1–9 year olds (TF1–9) <5%. Here we use program data to create an empirical model predicting the year of attaining global elimination of TF1–9. Methodology/Principal findings We calculated the mean number of years (95% CI) observed for an implementation unit (IU) to move from a baseline TF1–9 prevalence ≥5% to the elimination threshold, based on the region (Ethiopia vs. non-Ethiopia) and baseline prevalence category. Ethiopia IUs had significantly different rates of reaching the TF1–9 elimination threshold after a trachoma impact survey (TIS) compared to non-Ethiopia IUs across all baseline categories. We used those estimates to predict when remaining active trachoma-endemic IUs (TF1–9 ≥5%) would have their last round of mass drug administration (MDA) based on the mean number of years required and number of MDA rounds already completed. Our model predicts that elimination of TF1–9 will be achieved in 2028 in Ethiopia (95% CI: 2026–2033) and 2029 outside of Ethiopia (95% CI: 2023–2034), with some IUs in East Africa predicted to be the last requiring MDA globally. Conclusions/Significance Our empirical estimate is similar to those resulting from previous susceptible-infectious-susceptible (SIS) and mathematical models, suggesting that the forecast achievement of TF1–9 elimination is realistic with the caveat that although disease elimination progress can be predicted for most IUs, there is an important minority of IUs that is not declining or has not yet started trachoma elimination activities. These IUs represent an important barrier to the timely global elimination of active trachoma. |
Audience | Academic |
Author | Hooper, P. J Ngondi, Jeremiah M Emerson, Paul M Renneker, Kristen K |
AuthorAffiliation | 2 RTI International, Washington DC, United States of America 1 International Trachoma Initiative, The Task Force for Global Health, Decatur, Georgia, United States of America The University of Hong Kong, CHINA |
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Cites_doi | 10.3109/09286586.2015.1081249 10.1093/infdis/jir257 10.1787/9789264303201-3-en 10.1016/S0140-6736(11)61515-8 10.1001/jama.299.7.778 10.1371/journal.pntd.0004000 10.1016/S2214-109X(22)00050-X 10.1016/j.epidem.2017.01.007 10.1016/j.ophtha.2019.11.001 10.1093/trstmh/traa170 10.3109/09286586.2015.1037401 10.1093/cid/ciy004 |
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Copyright | COPYRIGHT 2022 Public Library of Science 2022 Renneker et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2022 Renneker et al 2022 Renneker et al |
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Notes | new_version ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 I have read the journal’s policy and the authors of this manuscript have the following competing interests: KKR, PME, and PJH are employees of International Trachoma Initiative, a program of The Task Force for Global Health, which receives an operating budget and research funds from Pfizer Inc., the manufacturers of Zithromax (azithromycin). |
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References | (pntd.0010563.ref019) 2017 AW Solomon (pntd.0010563.ref014) 2015; 22 A Amza (pntd.0010563.ref021) 2017; 64 Word Health Organization (pntd.0010563.ref002) 2021; 96 EM Harding-Esch (pntd.0010563.ref015) 2018 pntd.0010563.ref001 TM Lietman (pntd.0010563.ref023) 2020; 127 pntd.0010563.ref026 pntd.0010563.ref006 SK West (pntd.0010563.ref005) 2011; 204 H. Wickham (pntd.0010563.ref020) 2016 World Health Organization (pntd.0010563.ref003) 2020 World Health Organization (pntd.0010563.ref007) 2015 A Pinsent (pntd.0010563.ref013) 2017; 18 S Blumberg (pntd.0010563.ref027) 2021; 115 pntd.0010563.ref008 KK Renneker (pntd.0010563.ref004) 2022; 10 pntd.0010563.ref009 Expanded Special Project for Elimination of Neglected Tropical Diseases (pntd.0010563.ref028) 2020 F Liu (pntd.0010563.ref012) 2015; 9 International Trachoma Initiative (pntd.0010563.ref017) 2020 T Gebre (pntd.0010563.ref022) 2012; 379 M Melese (pntd.0010563.ref024) 2008; 299 TM Lietman (pntd.0010563.ref010) 2018; 66 pntd.0010563.ref016 M Gambhir (pntd.0010563.ref011) 2015; 22 W Godwin (pntd.0010563.ref025) 2020 pntd.0010563.ref018 NA Fernandez-Santos (pntd.0010563.ref029) 2021; 12 pntd.0010563.ref030 |
References_xml | – volume: 22 start-page: 394 issue: 6 year: 2015 ident: pntd.0010563.ref011 article-title: Estimating the Future Impact of a Multi-Pronged Intervention Strategy on Ocular Disease Sequelae Caused by Trachoma: A Modeling Study publication-title: Ophthalmic Epidemiol doi: 10.3109/09286586.2015.1081249 contributor: fullname: M Gambhir – ident: pntd.0010563.ref030 – volume: 204 start-page: 268 issue: 2 year: 2011 ident: pntd.0010563.ref005 article-title: Number of years of annual mass treatment with azithromycin needed to control trachoma in hyper-endemic communities in Tanzania publication-title: J Infect Dis doi: 10.1093/infdis/jir257 contributor: fullname: SK West – ident: pntd.0010563.ref001 – ident: pntd.0010563.ref018 doi: 10.1787/9789264303201-3-en – year: 2017 ident: pntd.0010563.ref019 publication-title: London School of Hygiene and Tropical Medicine. Trachoma in the Pacific: Research progress – year: 2016 ident: pntd.0010563.ref020 publication-title: Elegant Graphics for Data Analysis contributor: fullname: H. Wickham – volume: 379 start-page: 143 issue: 9811 year: 2012 ident: pntd.0010563.ref022 article-title: Comparison of annual versus twice-yearly mass azithromycin treatment for hyperendemic trachoma in Ethiopia: a cluster-randomised trial publication-title: Lancet doi: 10.1016/S0140-6736(11)61515-8 contributor: fullname: T Gebre – volume: 299 start-page: 778 issue: 7 year: 2008 ident: pntd.0010563.ref024 article-title: Comparison of annual and biannual mass antibiotic administration for elimination of infectious trachoma publication-title: Jama doi: 10.1001/jama.299.7.778 contributor: fullname: M Melese – ident: pntd.0010563.ref009 – volume: 9 start-page: e0004000 issue: 8 year: 2015 ident: pntd.0010563.ref012 article-title: Short-term Forecasting of the Prevalence of Trachoma: Expert Opinion, Statistical Regression, versus Transmission Models publication-title: PLoS Negl Trop Dis doi: 10.1371/journal.pntd.0004000 contributor: fullname: F Liu – volume: 10 start-page: e491 issue: 4 year: 2022 ident: pntd.0010563.ref004 article-title: Global progress toward the elimination of active trachoma: an analysis of 38 countries publication-title: The Lancet Global Health doi: 10.1016/S2214-109X(22)00050-X contributor: fullname: KK Renneker – year: 2020 ident: pntd.0010563.ref025 article-title: Trachoma Prevalence After Discontinuation of Mass Azithromycin Distribution publication-title: J Infect Dis contributor: fullname: W Godwin – ident: pntd.0010563.ref026 – volume: 96 start-page: 353 issue: 31 year: 2021 ident: pntd.0010563.ref002 publication-title: Weekly Epidemiological Record contributor: fullname: Word Health Organization – ident: pntd.0010563.ref016 – start-page: 2014 volume-title: Task Force for Global Health year: 2015 ident: pntd.0010563.ref007 contributor: fullname: World Health Organization – volume: 64 start-page: 743 issue: 6 year: 2017 ident: pntd.0010563.ref021 article-title: A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children publication-title: Clinical Infectious Diseases contributor: fullname: A Amza – volume: 18 start-page: 48 year: 2017 ident: pntd.0010563.ref013 article-title: Probabilistic forecasts of trachoma transmission at the district level: A statistical model comparison publication-title: Epidemics doi: 10.1016/j.epidem.2017.01.007 contributor: fullname: A Pinsent – year: 2020 ident: pntd.0010563.ref017 publication-title: Global Atlas of Trachoma Decatur, Georgia contributor: fullname: International Trachoma Initiative – volume: 127 start-page: 11 issue: 1 year: 2020 ident: pntd.0010563.ref023 article-title: Trachoma: Time to Talk Eradication publication-title: Ophthalmology doi: 10.1016/j.ophtha.2019.11.001 contributor: fullname: TM Lietman – volume: 12 start-page: 235 year: 2021 ident: pntd.0010563.ref029 article-title: Historical Review and Cost-Effectiveness Assessment of the Programs to Eliminate Onchocerciasis and Trachoma in Mexico. publication-title: Res Rep Trop Med contributor: fullname: NA Fernandez-Santos – ident: pntd.0010563.ref008 – volume: 115 start-page: 222 issue: 3 year: 2021 ident: pntd.0010563.ref027 article-title: Implications of the COVID-19 pandemic in eliminating trachoma as a public health problem publication-title: Trans R Soc Trop Med Hyg doi: 10.1093/trstmh/traa170 contributor: fullname: S Blumberg – ident: pntd.0010563.ref006 – volume: 22 start-page: 214 issue: 3 year: 2015 ident: pntd.0010563.ref014 article-title: The Global Trachoma Mapping Project: Methodology of a 34-Country Population-Based Study publication-title: Ophthalmic Epidemiology doi: 10.3109/09286586.2015.1037401 contributor: fullname: AW Solomon – year: 2018 ident: pntd.0010563.ref015 article-title: Tropical Data: Prevalence Surveys for Elimination of Trachoma and other Negelcted Tropical Diseases publication-title: Proceedings of the 14th International Symposium on Human Chlamydial Infections contributor: fullname: EM Harding-Esch – volume-title: Elimination of Trachoma in Myanmar year: 2020 ident: pntd.0010563.ref003 contributor: fullname: World Health Organization – volume: 66 start-page: S275 issue: suppl_4 year: 2018 ident: pntd.0010563.ref010 article-title: Models of Trachoma Transmission and Their Policy Implications: From Control to Elimination publication-title: Clin Infect Dis doi: 10.1093/cid/ciy004 contributor: fullname: TM Lietman – volume-title: Recommendations for Safely Restarting MDA for NTDs in Settings with Heightened Risk of COVID-19 Community Transmission year: 2020 ident: pntd.0010563.ref028 contributor: fullname: Expanded Special Project for Elimination of Neglected Tropical Diseases |
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Snippet | Background Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to... Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to forecast when... BACKGROUNDGreat progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to... Mathematical and statistical models have been used to forecast the global decline of active trachoma prevalence as a result of interventions against the... BackgroundGreat progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to... Background Great progress has been made toward the elimination of trachoma as a public-health problem. Mathematical and statistical models have been used to... |
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Title | Forecasting the elimination of active trachoma: An empirical model |
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