Quantitative Visions of Reality at the Tick-Host Interface: Biochemistry, Genomics, Proteomics, and Transcriptomics as Measures of Complete Inventories of the Tick Sialoverse

Species have definitive genomes. Even so, the transcriptional and translational products of the genome are dynamic and subject to change over time. This is especially true for the proteins secreted by ticks at the tick-host feeding interface that represent a complex system known as the sialoverse. T...

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Published inFrontiers in cellular and infection microbiology Vol. 10; p. 574405
Main Author Mans, Ben J.
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 11.09.2020
Subjects
Cellular and Infection Microbiology
proteome
salivary gland
sialome
sialoverse
tick
transcriptome
salivary gland
tick
sialome
sialoverse
transcriptome
proteome
Online AccessGet full text
ISSN2235-2988
2235-2988
DOI10.3389/fcimb.2020.574405

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Abstract Species have definitive genomes. Even so, the transcriptional and translational products of the genome are dynamic and subject to change over time. This is especially true for the proteins secreted by ticks at the tick-host feeding interface that represent a complex system known as the sialoverse. The sialoverse represent all of the proteins derived from tick salivary glands for all tick species that may be involved in tick-host interaction and the modulation of the host's defense mechanisms. The current study contemplates the advances made over time to understand and describe the complexity present in the sialoverse. Technological advances at given periods in time allowed detection of functions, genes, and proteins enabling a deeper insight into the complexity of the sialoverse and a concomitant expansion in complexity with as yet, no end in sight. The importance of systematic classification of the sialoverse is highlighted with the realization that our coverage of transcriptome and proteome space remains incomplete, but that complete descriptions may be possible in the future. Even so, analysis and integration of the sialoverse into a comprehensive understanding of tick-host interactions may require further technological advances given the high level of expected complexity that remains to be uncovered.
AbstractList Species have definitive genomes. Even so, the transcriptional and translational products of the genome are dynamic and subject to change over time. This is especially true for the proteins secreted by ticks at the tick-host feeding interface that represent a complex system known as the sialoverse. The sialoverse represent all of the proteins derived from tick salivary glands for all tick species that may be involved in tick-host interaction and the modulation of the host's defense mechanisms. The current study contemplates the advances made over time to understand and describe the complexity present in the sialoverse. Technological advances at given periods in time allowed detection of functions, genes, and proteins enabling a deeper insight into the complexity of the sialoverse and a concomitant expansion in complexity with as yet, no end in sight. The importance of systematic classification of the sialoverse is highlighted with the realization that our coverage of transcriptome and proteome space remains incomplete, but that complete descriptions may be possible in the future. Even so, analysis and integration of the sialoverse into a comprehensive understanding of tick-host interactions may require further technological advances given the high level of expected complexity that remains to be uncovered.
Species have definitive genomes. Even so, the transcriptional and translational products of the genome are dynamic and subject to change over time. This is especially true for the proteins secreted by ticks at the tick-host feeding interface that represent a complex system known as the sialoverse. The sialoverse represent all of the proteins derived from tick salivary glands for all tick species that may be involved in tick-host interaction and the modulation of the host's defense mechanisms. The current study contemplates the advances made over time to understand and describe the complexity present in the sialoverse. Technological advances at given periods in time allowed detection of functions, genes, and proteins enabling a deeper insight into the complexity of the sialoverse and a concomitant expansion in complexity with as yet, no end in sight. The importance of systematic classification of the sialoverse is highlighted with the realization that our coverage of transcriptome and proteome space remains incomplete, but that complete descriptions may be possible in the future. Even so, analysis and integration of the sialoverse into a comprehensive understanding of tick-host interactions may require further technological advances given the high level of expected complexity that remains to be uncovered.Species have definitive genomes. Even so, the transcriptional and translational products of the genome are dynamic and subject to change over time. This is especially true for the proteins secreted by ticks at the tick-host feeding interface that represent a complex system known as the sialoverse. The sialoverse represent all of the proteins derived from tick salivary glands for all tick species that may be involved in tick-host interaction and the modulation of the host's defense mechanisms. The current study contemplates the advances made over time to understand and describe the complexity present in the sialoverse. Technological advances at given periods in time allowed detection of functions, genes, and proteins enabling a deeper insight into the complexity of the sialoverse and a concomitant expansion in complexity with as yet, no end in sight. The importance of systematic classification of the sialoverse is highlighted with the realization that our coverage of transcriptome and proteome space remains incomplete, but that complete descriptions may be possible in the future. Even so, analysis and integration of the sialoverse into a comprehensive understanding of tick-host interactions may require further technological advances given the high level of expected complexity that remains to be uncovered.
Author Mans, Ben J.
AuthorAffiliation 1 Epidemiology, Parasites and Vectors, Agricultural Research Council-Onderstepoort Veterinary Research , Pretoria , South Africa
3 Department of Life and Consumer Sciences, University of South Africa , Pretoria , South Africa
2 Department of Veterinary Tropical Diseases, University of Pretoria , Pretoria , South Africa
AuthorAffiliation_xml – name: 2 Department of Veterinary Tropical Diseases, University of Pretoria , Pretoria , South Africa
– name: 1 Epidemiology, Parasites and Vectors, Agricultural Research Council-Onderstepoort Veterinary Research , Pretoria , South Africa
– name: 3 Department of Life and Consumer Sciences, University of South Africa , Pretoria , South Africa
Author_xml – sequence: 1
  givenname: Ben J.
  surname: Mans
  fullname: Mans, Ben J.
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Cites_doi 10.1126/science.2333510
10.1006/bbrc.1996.5948
10.12688/f1000research.13635.1
10.1016/j.gene.2015.01.019
10.1016/j.meegid.2015.03.010
10.1186/s12864-019-6042-1
10.1002/psc.3052
10.1016/j.jprot.2008.07.006
10.1016/j.parint.2016.10.011
10.1371/journal.pone.0094831
10.1051/parasite/2019018
10.1007/BF00052551
10.1023/A:1006362929841
10.1371/journal.pntd.0004323
10.3389/fimmu.2019.01056
10.1186/1756-3305-7-430
10.1016/S0041-0101(02)00098-3
10.1016/j.ibmb.2012.01.003
10.1371/journal.pone.0000451
10.1016/j.ibmb.2004.07.002
10.1016/j.ibmb.2007.07.003
10.1038/nature08909
10.1016/j.ibmb.2004.10.009
10.1007/978-3-319-40740-1_17
10.3390/vaccines8010091
10.1074/jbc.M112060200
10.1016/S0021-9258(17)37432-X
10.1038/nrg3068
10.4269/ajtmh.2000.62.99
10.2307/3278433
10.1111/brv.12384
10.2307/3281330
10.1038/ncomms10507
10.1016/j.ttbdis.2016.08.011
10.1186/s13071-019-3318-x
10.1016/j.molbiopara.2006.09.006
10.3389/fphys.2019.00318
10.1046/j.1365-2583.2002.00375.x
10.1093/jmedent/9.2.143
10.1645/0022-3395(2000)086[0516:IAMCOA]2.0.CO;2
10.1093/nar/gky1106
10.1016/j.ttbdis.2014.08.002
10.1186/1471-2164-14-135
10.1086/323351
10.1074/mcp.M114.039289
10.1016/j.meegid.2019.104008
10.2741/s504
10.3389/fcimb.2019.00477
10.1016/j.ijpara.2017.07.007
10.1016/j.ttbdis.2020.101427
10.1046/j.0269-283x.2001.00328.x
10.1371/journal.pone.0131292
10.1016/j.ibmb.2005.05.007
10.1186/1471-2164-11-450
10.1002/1522-2683(200105)22:9<1739::AID-ELPS1739>3.0.CO;2-7
10.1016/j.ttbdis.2018.03.024
10.1016/j.ibmb.2007.09.009
10.1038/nchem.2744
10.2144/96213pf02
10.3389/fcimb.2020.00374
10.1093/molbev/msg126
10.1186/s13071-018-3062-7
10.1016/j.ttbdis.2016.02.002
10.1038/s41598-019-49641-9
10.1111/cmi.12987
10.1046/j.0962-1075.2001.00311.x
10.1093/jmedent/10.4.355
10.1016/S1097-2765(00)80359-7
10.1093/nar/gku1117
10.1261/rna.061168.117
10.1093/nar/17.13.5409
10.1016/j.ibmb.2005.01.020
10.1016/S0006-291X(03)00857-X
10.1016/j.pt.2019.06.014
10.1111/j.1439-0450.1986.tb00025.x
10.1016/j.mcp.2016.02.006
10.1096/fj.13-232140
10.1186/s13071-017-2008-9
10.1186/s13071-017-2312-4
10.1016/j.dci.2017.10.012
10.1111/j.1365-2583.2009.00863.x
10.1016/S0965-1748(98)00034-4
10.1023/B:APPA.0000030012.47964.b3
10.1016/j.ttbdis.2016.04.006
10.1645/GE-1371.1
10.1016/S0020-7519(02)00159-5
10.1016/j.jprot.2013.01.015
10.1016/j.ibmb.2005.11.005
10.1038/srep09103
10.1016/j.ijpara.2014.07.003
10.1016/0040-8166(81)90003-3
10.1242/jcs.224212
10.1016/j.pt.2018.04.001
10.1242/jeb.137315
10.1146/annurev-genom-083115-022413
10.1016/j.jprot.2020.103899
10.1038/s41598-019-42899-z
10.1186/s12864-015-1981-7
10.1016/j.ibmb.2007.09.003
10.1016/S0065-2806(09)37002-2
10.3389/fcimb.2017.00413
10.1016/j.sbi.2013.02.013
10.1186/1471-2164-12-136
10.1016/j.ijpara.2017.03.007
10.1186/s13071-018-2932-3
10.1016/S0965-1748(01)00169-2
10.1007/BF00052809
10.1242/jeb.205.18.2843
10.1016/j.dib.2019.104602
10.1016/S0021-9258(18)53342-1
10.1016/S0965-1748(03)00083-3
10.1016/j.ijpara.2017.08.018
10.1186/s13071-015-0918-y
10.1074/mcp.M115.051938
10.1016/0040-8166(82)90035-0
10.2741/3363
10.1371/journal.pntd.0006410
10.1007/s12010-015-1688-x
10.1371/journal.pone.0089564
10.1093/molbev/msx319
10.1186/1471-2164-12-328
10.3389/fphys.2019.00530
10.1603/ME11215
10.1074/jbc.M001486200
10.1038/227680a0
10.2307/3281836
10.1016/S0021-9258(18)53341-X
10.1182/blood-2001-12-0237
10.1016/j.jprot.2014.12.014
10.3389/fphys.2019.00529
10.4269/ajtmh.2002.66.225
10.1074/jbc.271.30.17785
10.1186/1471-2164-9-233
10.1016/j.tibs.2016.08.008
10.1038/1841078a0
10.2478/s11686-019-00103-2
10.1016/0041-0101(83)90219-2
10.1016/S0021-9258(19)41496-8
10.1016/j.ttbdis.2013.05.001
10.1017/S0031182000003073
10.1073/pnas.2000605117
10.3390/biom10040555
10.1016/S0020-7519(02)00027-9
10.1016/j.pt.2019.06.012
10.1016/S0303-7207(98)00073-2
10.1023/A:1006198713791
10.1016/0041-0101(66)90003-1
10.3389/fcimb.2017.00476
10.3390/vetsci5020053
10.1016/j.pt.2009.03.005
10.1016/j.ibmb.2006.10.002
10.1016/j.ttbdis.2016.01.014
10.1016/j.jprot.2011.07.015
10.1016/j.ibmb.2003.09.002
10.1006/expr.1999.4448
10.1038/s41467-018-06214-0
10.1186/s13071-018-2874-9
10.1016/j.dci.2008.09.011
10.1007/s10493-019-00390-4
10.1016/j.jprot.2014.03.011
10.1016/S0965-1748(02)00047-4
10.1186/s13071-019-3864-2
10.1603/0022-2585-40.6.890
10.1186/1471-2164-15-518
10.1371/journal.pntd.0007758
10.1007/s10493-010-9392-6
10.1007/s10493-012-9604-3
10.1023/A:1025342015065
10.1371/journal.pone.0028525
10.1017/S003118200008077X
10.1016/S0965-1748(02)00240-0
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Keywords salivary gland
tick
sialome
sialoverse
transcriptome
proteome
Language English
License Copyright © 2020 Mans.
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This article was submitted to Parasite and Host, a section of the journal Frontiers in Cellular and Infection Microbiology
Edited by: Lucas Tirloni, National Institute of Allergy and Infectious Diseases (NIH), United States
Reviewed by: Shahid Karim, University of Southern Mississippi, United States; Elisa Azuara-Liceaga, Universidad Autónoma de la Ciudad de México, Mexico
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References Luo (B85) 2019; 26
Thompson (B152) 2017; 9
Gulia-Nuss (B61) 2016; 7
Kaire (B69) 1966; 4
Bensaoud (B14) 2018; 11
Charrier (B20) 2018; 11
Ribeiro (B132) 2006; 36
Mudenda (B107) 2014; 44
Neitz (B114) 1987; 54
Nienaber (B117) 1999; 93
Aljamali (B2) 2009; 18
Nilsen (B118) 2010; 463
Crispell (B32) 2019; 10
Francischetti (B47) 2003; 305
Schwarz (B145) 2013; 27
Valenzuela (B161); 205
Miller (B105) 2018; 7
Francischetti (B50) 2009; 14
de Castro (B35) 2016; 7
Karczewski (B70) 1994; 269
Cramaro (B31) 2015; 16
Levy (B80) 2016; 17
Bullard (B18) 2016; 7
Gaspar (B54) 1995; 19
Guerrero (B59) 2019; 27
Bakkes (B7) 2018; 9
Chmelar (B27) 2008; 9
Kim (B75) 2020; 14
Shabareesh (B146) 2017; 23
Martin (B101) 2011; 12
Narasimhan (B110) 2002; 11
Olafson (B121) 2011; 53
Rabilloud (B129) 2020; 107
Ribeiro (B134) 2012; 42
Tan (B150) 2015; 117
Barrero (B9) 2017; 47
Franck (B52) 2020; 117
Tirloni (B156) 2014; 9
Díaz-Sánchez (B39) 2019; 35
Kretz (B77) 1989; 17
Buresova (B19) 2009; 33
Sangamnatdej (B142) 2002; 11
Valenzuela (B160) 2000; 275
de Castro (B36) 2017; 10
Wang (B171) 1996; 271
Ribeiro (B133) 2011; 12
Guo (B62) 2019; 75
Chenchik (B24) 1996; 21
Xu (B176) 2015; 32
Barrero (B10) 2011; 12
Oleaga (B122) 2007; 37
Tress (B157) 2017; 42
Viljoen (B164) 1986; 72
Mans (B99) 2004; 33
Tirloni (B155) 2020
Villar (B167) 2014; 9
Giraldo-Calderón (B58) 2015; 43
Light (B81) 2013; 23
Till (B153) 1959; 184
Feng (B44) 2019; 78
Mans (B95) 2003; 20
Mans (B96); 100
Karim (B71) 2015; 10
Neitz (B111) 1983; 3
Xu (B175) 2003; 40
Ren (B131) 2019; 12
Ribeiro (B135) 2017; 8
Guerrero (B60) 2005; 35
Urbanová (B159) 2018; 79
Coons (B28) 1973; 59
Valenzuela (B162); 32
Garcia (B53) 2014; 7
Neitz (B113) 1969; 22
Oliveira (B123) 2013; 4
Nene (B115) 2004; 34
Moreira (B106) 2017; 66
Rosendale (B140) 2016; 219
Schwarz (B144) 2014; 13
Guo (B63) 1998; 139
Fawcett (B43) 1981; 13
Luo (B84) 2015; 564
Howell (B67) 1975; 43
McKeever (B103) 2009; 25
Antunes (B5) 2019; 10
Couto (B29) 2020; 8
Martins (B102) 2019; 10
Villar (B166) 2020; 10
Wang (B169) 1999; 23
Mulenga (B108) 2003; 33
Robinson (B138) 1913; 6
Vechtova (B163) 2018; 11
Shao (B147) 2015; 176
De Marco (B37) 2017; 31
McSwain (B104) 1982; 68
Joubert (B68) 1998; 22
Fawcett (B42) 1982; 14
Mans (B89) 2019; 10
Perner (B126) 2018; 12
Baxter (B11) 1998; 28
Charrier (B21) 2019; 9
Leboulle (B79) 2002; 66
Das (B33) 2001; 184
Alarcon-Chaidez (B1) 2007; 37
Suppan (B148) 2018; 93
Pienaar (B127) 2018; 5
Tabish (B149) 2006; 150
Wang (B168) 2001; 15
Araujo (B6) 2019; 9
Kotsyfakis (B76) 2015; 5
Mans (B100) 2001; 22
Bergman (B15) 2000; 86
Neitz (B112) 1986; 33
Malik (B87) 2019; 12
Giachetto (B56) 2020; 9
Radulović (B130) 2014; 15
Esteves (B40) 2017; 7
Madden (B86) 2002; 28
Bourret (B17) 2019; 21
Mans (B94); 277
Mans (B98); 40
Mans (B97); 34
Chinery (B26) 1973; 10
Waterhouse (B172) 2018; 35
Bishop (B16) 2002; 32
Karim (B72) 2011; 6
Temeyer (B151) 2012; 49
Villar (B165) 2015; 14
Estrada-Peña (B41) 2008; 94
Waxman (B174) 1990; 248
Bensaoud (B13); 35
Balashov (B8) 1972; 8
Bensaoud (B12); 20
Perez-Riverol (B125) 2019; 47
Andreotti (B4) 2018; 10
Chávez (B23) 2019; 132
Díaz-Martín (B38) 2013; 80
Gaspar (B55) 1996; 20
Mans (B91) 2016; 7
Saravanan (B143) 2003; 33
Tirloni (B154) 2015; 8
Narasimhan (B109) 2007; 2
Porter (B128) 2015; 6
Francischetti (B45) 2011; 74
Ribeiro (B136) 2009; 37
Das (B34) 2000; 62
Waxman (B173) 1993; 268
Kim (B74) 2016; 10
Anatriello (B3) 2010; 11
Mans (B90) 2008; 38
Laemmli (B78) 1970; 227
Lukyanov (B83) 1997; 230
Mans (B88) 2016
Chinery (B25) 1965; 22
Francischetti (B48); 71
Nene (B116) 2002; 32
Francischetti (B51) 2002; 99
Gibson (B57) 2013; 14
Untalan (B158) 2005; 35
Ribeiro (B137) 2020; 10
Keller (B73) 1993; 268
Liu (B82) 2020; 11
Wang (B170) 1994; 109
Francischetti (B49) 2005; 35
Roshdy (B141) 1972; 9
O'Farrell (B120) 1975; 250
Cramaro (B30) 2017; 10
Rodriguez-Valle (B139) 2018; 48
Chattopadhyay (B22) 2018; 9
Mans (B93); 32
Hollmann (B66) 2018; 48
Hackenberg (B64) 2018; 34
Zhou (B177) 2013; 59
Paesen (B124) 1999; 3
Francischetti (B46); 38
Mans (B92) 2017; 7
Hackenberg (B65) 2017; 23
Niu (B119) 2019; 64
References_xml – volume: 248
  start-page: 593
  year: 1990
  ident: B174
  article-title: Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa
  publication-title: Science
  doi: 10.1126/science.2333510
– volume: 230
  start-page: 285
  year: 1997
  ident: B83
  article-title: Construction of cDNA libraries from small amounts of total RNA using the suppression PCR effect
  publication-title: Biochem. Biophys. Res. Commun
  doi: 10.1006/bbrc.1996.5948
– volume: 7
  start-page: 297
  year: 2018
  ident: B105
  article-title: A draft genome sequence for the Ixodes scapularis cell line, ISE6
  publication-title: F1000Res
  doi: 10.12688/f1000research.13635.1
– volume: 564
  start-page: 125
  year: 2015
  ident: B84
  article-title: Identification and characterization of microRNAs by deep-sequencing in Hyalomma anatolicum anatolicum (Acari: Ixodidae) ticks
  publication-title: Gene
  doi: 10.1016/j.gene.2015.01.019
– volume: 32
  start-page: 135
  year: 2015
  ident: B176
  article-title: De novo sequencing, assembly and analysis of salivary gland transcriptome of Haemaphysalis flava and identification of sialoprotein genes
  publication-title: Infect. Genet. Evol
  doi: 10.1016/j.meegid.2015.03.010
– volume: 20
  start-page: 675
  ident: B12
  article-title: Proteomic informed by transcriptomic for salivary glands components of the camel tick Hyalomma dromedarii
  publication-title: BMC Genomics
  doi: 10.1186/s12864-019-6042-1
– volume: 23
  start-page: 880
  year: 2017
  ident: B146
  article-title: Structural and functional studies of differentially O-glycosylated analogs of a thrombin inhibitory peptide - variegin
  publication-title: J. Pept. Sci
  doi: 10.1002/psc.3052
– volume: 71
  start-page: 493
  ident: B48
  article-title: An insight into the salivary transcriptome and proteome of the soft tick and vector of epizootic bovine abortion, Ornithodoros coriaceus
  publication-title: J. Proteomics
  doi: 10.1016/j.jprot.2008.07.006
– volume: 66
  start-page: 64
  year: 2017
  ident: B106
  article-title: A deep insight into the whole transcriptome of midguts, ovaries and salivary glands of the Amblyomma sculptum tick
  publication-title: Parasitol. Int
  doi: 10.1016/j.parint.2016.10.011
– volume: 9
  start-page: e94831
  year: 2014
  ident: B156
  article-title: Proteomic analysis of cattle tick Rhipicephalus (Boophilus) microplus saliva: a comparison between partially and fully engorged females
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0094831
– volume: 26
  start-page: 18
  year: 2019
  ident: B85
  article-title: Comparative analysis of microRNA profiles between wild and cultured Haemaphysalis longicornis (Acari, Ixodidae) ticks
  publication-title: Parasite
  doi: 10.1051/parasite/2019018
– volume: 19
  start-page: 117
  year: 1995
  ident: B54
  article-title: Identification of anticoagulant activities in the salivary glands of the soft tick, Ornithodoros savignyi
  publication-title: Exp. Appl. Acarol
  doi: 10.1007/BF00052551
– volume: 23
  start-page: 969
  year: 1999
  ident: B169
  article-title: Molecular individuality: polymorphism of salivary gland proteins in three species of ixodid tick
  publication-title: Exp. Appl. Acarol
  doi: 10.1023/A:1006362929841
– volume: 10
  start-page: e0004323
  year: 2016
  ident: B74
  article-title: Ixodes scapularis tick saliva proteins sequentially secreted every 24 h during blood feeding
  publication-title: PLoS Negl. Trop. Dis
  doi: 10.1371/journal.pntd.0004323
– volume: 10
  start-page: 1056
  year: 2019
  ident: B32
  article-title: Discovery of alpha-gal-containing antigens in North American tick species believed to induce red meat allergy
  publication-title: Front. Immunol
  doi: 10.3389/fimmu.2019.01056
– volume: 7
  start-page: 430
  year: 2014
  ident: B53
  article-title: The sialotranscriptome of Amblyomma triste, Amblyomma parvum and Amblyomma cajennense ticks, uncovered by 454-based RNA-seq
  publication-title: Parasit. Vectors
  doi: 10.1186/1756-3305-7-430
– volume: 40
  start-page: 1007
  ident: B98
  article-title: Pathogenic mechanisms of sand tampan toxicoses induced by the tick, Ornithodoros savignyi
  publication-title: Toxicon
  doi: 10.1016/S0041-0101(02)00098-3
– volume: 42
  start-page: 332
  year: 2012
  ident: B134
  article-title: The sialotranscriptome of Antricola delacruzi female ticks is compatible with non-hematophagous behavior and an alternative source of food
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2012.01.003
– volume: 2
  start-page: e451
  year: 2007
  ident: B109
  article-title: Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0000451
– volume: 34
  start-page: 1117
  year: 2004
  ident: B115
  article-title: Genes transcribed in the salivary glands of female Rhipicephalus appendiculatus ticks infected with Theileria parva
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2004.07.002
– volume: 37
  start-page: 1149
  year: 2007
  ident: B122
  article-title: A proteomic approach to the identification of salivary proteins from the argasid ticks Ornithodoros moubata and Ornithodoros erraticus
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2007.07.003
– volume: 463
  start-page: 457
  year: 2010
  ident: B118
  article-title: Expansion of the eukaryotic proteome by alternative splicing
  publication-title: Nature
  doi: 10.1038/nature08909
– volume: 35
  start-page: 141
  year: 2005
  ident: B158
  article-title: Proteome analysis of abundantly expressed proteins from unfed larvae of the cattle tick, Boophilus microplus
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2004.10.009
– start-page: 625
  volume-title: Extracellular Composite Matrices in Arthropods
  year: 2016
  ident: B88
  article-title: “Glandular matrices and secretions: blood- feeding arthropods,”
  doi: 10.1007/978-3-319-40740-1_17
– volume: 8
  start-page: 91
  year: 2020
  ident: B29
  article-title: Quantitative proteomics identifies metabolic pathways affected by Babesia infection and blood feeding in the sialoproteome of the vector Rhipicephalus bursa
  publication-title: Vaccines
  doi: 10.3390/vaccines8010091
– volume: 277
  start-page: 21371
  ident: B94
  article-title: Savignygrin, a platelet aggregation inhibitor from the soft tick, Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold
  publication-title: J. Biol. Chem
  doi: 10.1074/jbc.M112060200
– volume: 269
  start-page: 6702
  year: 1994
  ident: B70
  article-title: Disagregin is a fibrinogen receptor antagonist lacking the Arg-Gly-Asp sequence from the tick, Ornithodoros moubata
  publication-title: J. Biol. Chem
  doi: 10.1016/S0021-9258(17)37432-X
– volume: 12
  start-page: 671
  year: 2011
  ident: B101
  article-title: Next-generation transcriptome assembly
  publication-title: Nat. Rev. Genet
  doi: 10.1038/nrg3068
– volume: 62
  start-page: 99
  year: 2000
  ident: B34
  article-title: Salp16, a gene induced in Ixodes scapularis salivary glands during tick feeding
  publication-title: Am. J. Trop. Med. Hyg
  doi: 10.4269/ajtmh.2000.62.99
– volume: 59
  start-page: 900
  year: 1973
  ident: B28
  article-title: Fine structure of the salivary glands of unfed male Dermacentor variabilis (say) (Ixodoidea: Ixodidae)
  publication-title: J. Parasitol
  doi: 10.2307/3278433
– volume: 93
  start-page: 1056
  year: 2018
  ident: B148
  article-title: Tick attachment cement - reviewing the mysteries of a biological skin plug system
  publication-title: Biol. Rev. Camb. Philos. Soc
  doi: 10.1111/brv.12384
– volume: 68
  start-page: 100
  year: 1982
  ident: B104
  article-title: Protein changes in the salivary glands of the female lone star tick, Amblyomma americanum, during feeding
  publication-title: J. Parasitol
  doi: 10.2307/3281330
– volume: 7
  start-page: 10507
  year: 2016
  ident: B61
  article-title: Genomic insights into the Ixodes scapularis tick vector of Lyme disease
  publication-title: Nat. Commun
  doi: 10.1038/ncomms10507
– volume: 8
  start-page: 201
  year: 2017
  ident: B135
  article-title: An insight into the sialome of Hyalomma excavatum
  publication-title: Ticks Tick Borne Dis
  doi: 10.1016/j.ttbdis.2016.08.011
– volume: 12
  start-page: 68
  year: 2019
  ident: B87
  article-title: A microRNA profile of saliva and role of miR-375 in Haemaphysalis longicornis (Ixodida: Ixodidae)
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-019-3318-x
– volume: 150
  start-page: 330
  year: 2006
  ident: B149
  article-title: Molecular characterisation of cAMP-dependent protein kinase (PK-A) catalytic subunit isoforms in the male tick, Amblyomma hebraeum
  publication-title: Mol. Biochem. Parasitol
  doi: 10.1016/j.molbiopara.2006.09.006
– volume: 10
  start-page: 318
  year: 2019
  ident: B5
  article-title: Transcriptome and proteome response of Rhipicephalus annulatus tick vector to Babesia bigemina infection
  publication-title: Front. Physiol
  doi: 10.3389/fphys.2019.00318
– volume: 11
  start-page: 641
  year: 2002
  ident: B110
  article-title: A novel family of anticoagulants from the saliva of Ixodes scapularis
  publication-title: Insect Mol. Biol
  doi: 10.1046/j.1365-2583.2002.00375.x
– volume: 9
  start-page: 143
  year: 1972
  ident: B141
  article-title: The subgenus Persicargas (Ixodoidea, Argasidae, Argas). 15. histology and histochemistry of the salivary glands of A. (P.) persicus (Oken)
  publication-title: J. Med. Entomol.
  doi: 10.1093/jmedent/9.2.143
– volume: 86
  start-page: 516
  year: 2000
  ident: B15
  article-title: Isolation and molecular cloning of a secreted immunosuppresant protein from Dermacentor andersoni salivary gland
  publication-title: J. Parasitol
  doi: 10.1645/0022-3395(2000)086[0516:IAMCOA]2.0.CO;2
– volume: 47
  start-page: D442
  year: 2019
  ident: B125
  article-title: The PRIDE database and related tools and resources in 2019: improving support for quantification data
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gky1106
– volume: 6
  start-page: 16
  year: 2015
  ident: B128
  article-title: Bioinformatic analyses of male and female Amblyomma americanum tick expressed serine protease inhibitors (serpins)
  publication-title: Ticks Tick Borne Dis
  doi: 10.1016/j.ttbdis.2014.08.002
– volume: 14
  start-page: 135
  year: 2013
  ident: B57
  article-title: Why so many unknown genes?
  publication-title: partitioning orphans from a representative transcriptome of the lone star tick Amblyomma americanum. BMC Genomics
  doi: 10.1186/1471-2164-14-135
– volume: 184
  start-page: 1056
  year: 2001
  ident: B33
  article-title: Salp25D, an Ixodes scapularis antioxidant, is 1 of 14 immunodominant antigens in engorged tick salivary glands
  publication-title: J. Infect. Dis
  doi: 10.1086/323351
– volume: 13
  start-page: 2725
  year: 2014
  ident: B144
  article-title: A systems level analysis reveals transcriptomic and proteomic complexity in Ixodes ricinus midgut and salivary glands during early attachment and feeding
  publication-title: Mol. Cell. Proteomics
  doi: 10.1074/mcp.M114.039289
– volume: 75
  start-page: 104008
  year: 2019
  ident: B62
  article-title: De novo transcriptome sequencing and comparative analysis of Haemaphysalis flava Neumann, 1897 at larvae and nymph stages
  publication-title: Infect. Genet. Evol
  doi: 10.1016/j.meegid.2019.104008
– volume: 10
  start-page: 127
  year: 2018
  ident: B4
  article-title: Advances in tick vaccinology in Brazil: from gene expression to immunoprotection
  publication-title: Front. Biosci.
  doi: 10.2741/s504
– volume: 9
  start-page: 477
  year: 2020
  ident: B56
  article-title: Gene expression in the salivary gland of Rhipicephalus (Boophilus) microplus fed on tick-susceptible and tick-resistant hosts
  publication-title: Front. Cell Infect. Microbiol
  doi: 10.3389/fcimb.2019.00477
– volume: 48
  start-page: 71
  year: 2018
  ident: B139
  article-title: Transcriptome and toxin family analysis of the paralysis tick, Ixodes holocyclus
  publication-title: Int. J. Parasitol
  doi: 10.1016/j.ijpara.2017.07.007
– volume: 11
  start-page: 101427
  year: 2020
  ident: B82
  article-title: Analysis of microRNA expression profiles dynamic in different life stages of Haemaphysalis longicornis ticks by deep sequencing of small RNA libraries
  publication-title: Ticks Tick Borne Dis
  doi: 10.1016/j.ttbdis.2020.101427
– volume: 15
  start-page: 403
  year: 2001
  ident: B168
  article-title: Molecular individuality and adaptation of the tick Rhipicephalus appendiculatus in changed feeding environments
  publication-title: Med. Vet. Entomol
  doi: 10.1046/j.0269-283x.2001.00328.x
– volume: 10
  start-page: e0131292
  year: 2015
  ident: B71
  article-title: An insight into the sialome of the Lone Star tick, Amblyomma americanum, with a glimpse on its time dependent gene expression
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0131292
– volume: 35
  start-page: 1142
  year: 2005
  ident: B49
  article-title: The transcriptome of the salivary glands of the female western black-legged tick Ixodes pacificus (Acari: Ixodidae)
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2005.05.007
– volume: 11
  start-page: 450
  year: 2010
  ident: B3
  article-title: An insight into the sialotranscriptome of the brown dog tick, Rhipicephalus sanguineus
  publication-title: BMC Genomics
  doi: 10.1186/1471-2164-11-450
– volume: 22
  start-page: 1739
  year: 2001
  ident: B100
  article-title: Identification of putative proteins involved in granule biogenesis of tick salivary glands
  publication-title: Electrophoresis
  doi: 10.1002/1522-2683(200105)22:9<1739::AID-ELPS1739>3.0.CO;2-7
– volume: 9
  start-page: 1006
  year: 2018
  ident: B7
  article-title: Integrative taxonomy of Afrotropical Ornithodoros (Ornithodoros) (Acari: Ixodida: Argasidae)
  publication-title: Ticks Tick Borne Dis.
  doi: 10.1016/j.ttbdis.2018.03.024
– volume: 38
  start-page: 1
  ident: B46
  article-title: An insight into the sialome of the soft tick, Ornithodorus parkeri
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2007.09.009
– volume: 9
  start-page: 909
  year: 2017
  ident: B152
  article-title: Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors
  publication-title: Nat. Chem
  doi: 10.1038/nchem.2744
– volume: 21
  start-page: 526
  year: 1996
  ident: B24
  article-title: Full-length cDNA cloning and determination of mRNA 5' and 3' ends by amplification of adaptor-ligated cDNA
  publication-title: Biotechniques
  doi: 10.2144/96213pf02
– volume: 10
  start-page: 374
  year: 2020
  ident: B137
  article-title: TickSialoFam (TSFam): a database that helps to classify tick salivary proteins, a review on tick salivary protein function and evolution, with considerations on the tick sialome switching phenomenon
  publication-title: Front. Cell. Infect. Microbiol
  doi: 10.3389/fcimb.2020.00374
– volume: 20
  start-page: 1158
  year: 2003
  ident: B95
  article-title: The major tick salivary gland proteins and toxins from the soft tick, Ornithodoros savignyi, are part of the tick Lipocalin family: implications for the origins of tick toxicoses
  publication-title: Mol. Biol. Evol
  doi: 10.1093/molbev/msg126
– volume: 11
  start-page: 594
  year: 2018
  ident: B163
  article-title: A bite so sweet: the glycobiology interface of tick-host-pathogen interactions
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-018-3062-7
– volume: 7
  start-page: 509
  year: 2016
  ident: B91
  article-title: Ancestral reconstruction of tick lineages
  publication-title: Ticks Tick Borne Dis
  doi: 10.1016/j.ttbdis.2016.02.002
– volume: 9
  start-page: 12923
  year: 2019
  ident: B21
  article-title: A transcriptome-based phylogenetic study of hard ticks (Ixodidae)
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-019-49641-9
– volume: 21
  start-page: e12987
  year: 2019
  ident: B17
  article-title: The relapsing fever spirochete Borrelia turicatae persists in the highly oxidative environment of its soft-bodied tick vector
  publication-title: Cell. Microbiol
  doi: 10.1111/cmi.12987
– volume: 11
  start-page: 79
  year: 2002
  ident: B142
  article-title: A high affinity serotonin- and histamine-binding lipocalin from tick saliva
  publication-title: Insect Mol. Biol
  doi: 10.1046/j.0962-1075.2001.00311.x
– volume: 10
  start-page: 355
  year: 1973
  ident: B26
  article-title: The nature and origin of the “cement” substance at the site of attachment and feeding of adult Haemaphysalis spinigera (Ixodidae)
  publication-title: J. Med. Entomol
  doi: 10.1093/jmedent/10.4.355
– volume: 3
  start-page: 661
  year: 1999
  ident: B124
  article-title: Tick histamine-binding proteins: isolation, cloning, and three dimensional structure
  publication-title: Mol. Cell
  doi: 10.1016/S1097-2765(00)80359-7
– volume: 43
  start-page: D707
  year: 2015
  ident: B58
  article-title: VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/gku1117
– volume: 23
  start-page: 1259
  year: 2017
  ident: B65
  article-title: In silico target network analysis of de novo-discovered, tick saliva-specific microRNAs reveals important combinatorial effects in their interference with vertebrate host physiology
  publication-title: RNA
  doi: 10.1261/rna.061168.117
– volume: 17
  start-page: 5409
  year: 1989
  ident: B77
  article-title: Effect of lambda packaging extract mcr restriction activity on DNA cloning
  publication-title: Nucleic Acids Res
  doi: 10.1093/nar/17.13.5409
– volume: 35
  start-page: 585
  year: 2005
  ident: B60
  article-title: BmiGI: a database of cDNAs expressed in Boophilus microplus, the tropical/southern cattle tick
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2005.01.020
– volume: 305
  start-page: 869
  year: 2003
  ident: B47
  article-title: Cloning of a salivary gland metalloprotease and characterization of gelatinase and fibrin(ogen)lytic activities in the saliva of the Lyme disease tick vector Ixodes scapularis
  publication-title: Biochem. Biophys. Res. Commun
  doi: 10.1016/S0006-291X(03)00857-X
– volume: 35
  start-page: 725
  year: 2019
  ident: B39
  article-title: Evolutionary insights into the tick hologenome
  publication-title: Trends Parasitol
  doi: 10.1016/j.pt.2019.06.014
– volume: 33
  start-page: 213
  year: 1986
  ident: B112
  article-title: Changes in the protein pattern in the salivary glands of paralysis inducing female Rhipicephalus evertsi evertsi during infestation
  publication-title: Zentralbl. Veterinarmed. B
  doi: 10.1111/j.1439-0450.1986.tb00025.x
– volume: 31
  start-page: 85
  year: 2017
  ident: B37
  article-title: Transcriptome of larvae representing the Rhipicephalus sanguineus complex
  publication-title: Mol. Cell. Probes
  doi: 10.1016/j.mcp.2016.02.006
– volume: 27
  start-page: 4745
  year: 2013
  ident: B145
  article-title: De novo Ixodes ricinus salivary gland transcriptome analysis using two next-generation sequencing methodologies
  publication-title: FASEB J
  doi: 10.1096/fj.13-232140
– volume: 10
  start-page: 71
  year: 2017
  ident: B30
  article-title: Genome scaffolding and annotation for the pathogen vector Ixodes ricinus by ultra-long single molecule sequencing
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-017-2008-9
– volume: 10
  start-page: 384
  year: 2017
  ident: B36
  article-title: Sialotranscriptomics of Rhipicephalus zambeziensis reveals intricate expression profiles of secretory proteins and suggests tight temporal transcriptional regulation during blood-feeding
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-017-2312-4
– volume: 79
  start-page: 86
  year: 2018
  ident: B159
  article-title: IrC2/Bf - A yeast and Borrelia responsive component of the complement system from the hard tick Ixodes ricinus
  publication-title: Dev. Comp. Immunol
  doi: 10.1016/j.dci.2017.10.012
– volume: 18
  start-page: 129
  year: 2009
  ident: B2
  article-title: Transcriptome analysis of the salivary glands of the female tick Amblyomma americanum (Acari: Ixodidae)
  publication-title: Insect Mol. Biol.
  doi: 10.1111/j.1365-2583.2009.00863.x
– volume: 28
  start-page: 581
  year: 1998
  ident: B11
  article-title: Acetylcholinesterase cDNA of the cattle tick, Boophilus microplus: characterisation and role in organophosphate resistance
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/S0965-1748(98)00034-4
– volume: 33
  start-page: 119
  year: 2004
  ident: B99
  article-title: A reassessment of argasid tick salivary gland ultrastructure from an immuno-cytochemical perspective
  publication-title: Exp. Appl. Acarol
  doi: 10.1023/B:APPA.0000030012.47964.b3
– volume: 7
  start-page: 880
  year: 2016
  ident: B18
  article-title: Structural characterization of tick cement cones collected from in vivo and artificial membrane blood-fed lone star ticks (Amblyomma americanum)
  publication-title: Ticks Tick Borne Dis.
  doi: 10.1016/j.ttbdis.2016.04.006
– volume: 94
  start-page: 953
  year: 2008
  ident: B41
  article-title: Observations on Antricola ticks: small nymphs feed on mammalian hosts and have a salivary gland structure similar to ixodid ticks
  publication-title: J. Parasitol
  doi: 10.1645/GE-1371.1
– volume: 32
  start-page: 1447
  year: 2002
  ident: B116
  article-title: AvGI, an index of genes transcribed in the salivary glands of the ixodid tick Amblyomma variegatum
  publication-title: Int. J. Parasitol
  doi: 10.1016/S0020-7519(02)00159-5
– volume: 80
  start-page: 216
  year: 2013
  ident: B38
  article-title: An insight into the proteome of the saliva of the argasid tick Ornithodoros moubata reveals important differences in saliva protein composition between the sexes
  publication-title: J. Proteomics
  doi: 10.1016/j.jprot.2013.01.015
– volume: 36
  start-page: 111
  year: 2006
  ident: B132
  article-title: An annotated catalog of salivary gland transcripts from Ixodes scapularis ticks
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2005.11.005
– volume: 5
  start-page: 9103
  year: 2015
  ident: B76
  article-title: Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host
  publication-title: Sci. Rep
  doi: 10.1038/srep09103
– volume: 44
  start-page: 1029
  year: 2014
  ident: B107
  article-title: Proteomics informed by transcriptomics identifies novel secreted proteins in Dermacentor andersoni saliva
  publication-title: Int. J. Parasitol
  doi: 10.1016/j.ijpara.2014.07.003
– volume: 13
  start-page: 231
  year: 1981
  ident: B43
  article-title: Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. II. cellular basis for fluid secretion in the type III acinus
  publication-title: Tissue Cell
  doi: 10.1016/0040-8166(81)90003-3
– volume: 132
  start-page: jcs224212
  year: 2019
  ident: B23
  article-title: Message in a vesicle-trans-kingdom intercommunication at the vector-host interface
  publication-title: J. Cell Sci.
  doi: 10.1242/jcs.224212
– volume: 34
  start-page: 549
  year: 2018
  ident: B64
  article-title: Exosome-mediated pathogen transmission by arthropod vectors
  publication-title: Trends Parasitol
  doi: 10.1016/j.pt.2018.04.001
– volume: 219
  start-page: 1808
  year: 2016
  ident: B140
  article-title: Mechanistic underpinnings of dehydration stress in the American dog tick revealed through RNA-Seq and metabolomics
  publication-title: J. Exp. Biol
  doi: 10.1242/jeb.137315
– volume: 17
  start-page: 95
  year: 2016
  ident: B80
  article-title: Advancements in next-generation sequencing
  publication-title: Annu. Rev. Genomics Hum. Genet
  doi: 10.1146/annurev-genom-083115-022413
– start-page: 103899
  year: 2020
  ident: B155
  article-title: Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): insights into gene expression during blood feeding
  publication-title: J. Proteomics
  doi: 10.1016/j.jprot.2020.103899
– volume: 9
  start-page: 6764
  year: 2019
  ident: B6
  article-title: RNA-seq analysis of the salivary glands and midgut of the argasid tick Ornithodoros rostratus
  publication-title: Sci. Rep
  doi: 10.1038/s41598-019-42899-z
– volume: 16
  start-page: 871
  year: 2015
  ident: B31
  article-title: Integration of Ixodes ricinus genome sequencing with transcriptome and proteome annotation of the naïve midgut
  publication-title: BMC Genomics
  doi: 10.1186/s12864-015-1981-7
– volume: 38
  start-page: 42
  year: 2008
  ident: B90
  article-title: Comparative sialomics between hard and soft ticks: implications for the evolution of blood-feeding behavior
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2007.09.003
– volume: 37
  start-page: 59
  year: 2009
  ident: B136
  article-title: From sialomes to the sialoverse: an insight into salivary potion of blood-feeding insects
  publication-title: Adv. Insect Physiol
  doi: 10.1016/S0065-2806(09)37002-2
– volume: 7
  start-page: 413
  year: 2017
  ident: B92
  article-title: Gene duplication and protein evolution in tick-host interactions
  publication-title: Front. Cell Infect. Microbiol
  doi: 10.3389/fcimb.2017.00413
– volume: 23
  start-page: 451
  year: 2013
  ident: B81
  article-title: The impact of splicing on protein domain architecture
  publication-title: Curr. Opin. Struct. Biol
  doi: 10.1016/j.sbi.2013.02.013
– volume: 12
  start-page: 136
  year: 2011
  ident: B133
  article-title: A further insight into the sialome of the tropical bont tick, Amblyomma variegatum
  publication-title: BMC Genomics
  doi: 10.1186/1471-2164-12-136
– volume: 47
  start-page: 569
  year: 2017
  ident: B9
  article-title: Gene-enriched draft genome of the cattle tick Rhipicephalus microplus: assembly by the hybrid Pacific biosciences/illumina approach enabled analysis of the highly repetitive genome
  publication-title: Int. J. Parasitol
  doi: 10.1016/j.ijpara.2017.03.007
– volume: 11
  start-page: 364
  year: 2018
  ident: B20
  article-title: Whole body transcriptomes and new insights into the biology of the tick Ixodes ricinus
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-018-2932-3
– volume: 32
  start-page: 821
  ident: B93
  article-title: Amino acid sequence and structure modeling of savignin, a thrombin inhibitor from the tick, Ornithodoros savignyi
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/S0965-1748(01)00169-2
– volume: 22
  start-page: 321
  year: 1965
  ident: B25
  article-title: Studies on the various glands of the tick Haemaphysalis spinigera Neumann 1897. 3. the salivary glands
  publication-title: Acta Trop
– volume: 20
  start-page: 583
  year: 1996
  ident: B55
  article-title: Isolation and characterization of an anticoagulant from the salivary glands of the tick, Ornithodoros savignyi (Acari: Argasidae)
  publication-title: Exp. Appl. Acarol
  doi: 10.1007/BF00052809
– volume: 205
  start-page: 2843
  ident: B161
  article-title: Exploring the sialome of the tick Ixodes scapularis
  publication-title: J. Exp. Biol
  doi: 10.1242/jeb.205.18.2843
– volume: 27
  start-page: 104602
  year: 2019
  ident: B59
  article-title: The Pacific biosciences de novo assembled genome dataset from a parthenogenetic New Zealand wild population of the longhorned tick, Haemaphysalis longicornis Neumann, 1901
  publication-title: Data Brief
  doi: 10.1016/j.dib.2019.104602
– volume: 268
  start-page: 5450
  year: 1993
  ident: B73
  article-title: Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation
  publication-title: J. Biol. Chem
  doi: 10.1016/S0021-9258(18)53342-1
– volume: 33
  start-page: 841
  year: 2003
  ident: B143
  article-title: Molecular cloning, structure and bait region splice variants of alpha2-macroglobulin from the soft tick Ornithodoros moubata
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/S0965-1748(03)00083-3
– volume: 48
  start-page: 211
  year: 2018
  ident: B66
  article-title: Identification and characterization of proteins in the Amblyomma americanum tick cement cone
  publication-title: Int. J. Parasitol
  doi: 10.1016/j.ijpara.2017.08.018
– volume: 8
  start-page: 338
  year: 2015
  ident: B154
  article-title: Saliva from nymph and adult females of Haemaphysalis longicornis: a proteomic study
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-015-0918-y
– volume: 14
  start-page: 3154
  year: 2015
  ident: B165
  article-title: Integrated metabolomics, transcriptomics and proteomics identifies metabolic pathways affected by Anaplasma phagocytophilum infection in tick cells
  publication-title: Mol. Cell. Proteomics
  doi: 10.1074/mcp.M115.051938
– volume: 14
  start-page: 397
  year: 1982
  ident: B42
  article-title: Salivary gland of the tick vector of East Coast fever
  publication-title: IV. cell type selectivity and host cell responses to Theileria parva. Tissue Cell
  doi: 10.1016/0040-8166(82)90035-0
– volume: 14
  start-page: 2051
  year: 2009
  ident: B50
  article-title: The role of saliva in tick feeding
  publication-title: Front. Biosci.
  doi: 10.2741/3363
– volume: 12
  start-page: e0006410
  year: 2018
  ident: B126
  article-title: Sialome diversity of ticks revealed by RNAseq of single tick salivary glands
  publication-title: PLoS Negl. Trop. Dis
  doi: 10.1371/journal.pntd.0006410
– volume: 176
  start-page: 1928
  year: 2015
  ident: B147
  article-title: Comparative profiling of microRNAs in male and female Rhipicephalus sanguineus
  publication-title: Appl. Biochem. Biotechnol
  doi: 10.1007/s12010-015-1688-x
– volume: 9
  start-page: e89564
  year: 2014
  ident: B167
  article-title: A systems biology approach to the characterization of stress response in Dermacentor reticulatus tick unfed larvae
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0089564
– volume: 35
  start-page: 543
  year: 2018
  ident: B172
  article-title: BUSCO applications from quality assessments to gene prediction and phylogenomics
  publication-title: Mol. Biol. Evol
  doi: 10.1093/molbev/msx319
– volume: 12
  start-page: 328
  year: 2011
  ident: B10
  article-title: Evolutionary conserved microRNAs are ubiquitously expressed compared to tick-specific miRNAs in the cattle tick Rhipicephalus (Boophilus) microplus
  publication-title: BMC Genomics
  doi: 10.1186/1471-2164-12-328
– volume: 10
  start-page: 530
  year: 2019
  ident: B89
  article-title: Chemical equilibrium at the tick-host feeding interface: a critical examination of biological relevance in hematophagous behavior
  publication-title: Front. Physiol
  doi: 10.3389/fphys.2019.00530
– volume: 49
  start-page: 555
  year: 2012
  ident: B151
  article-title: Sequence polymorphism in acetylcholinesterase transcripts and genotyping survey of BmAchE1 in laboratory and Mexican strains of Rhipicephalus (Boophilus) microplus
  publication-title: J. Med. Entomol
  doi: 10.1603/ME11215
– volume: 275
  start-page: 18717
  year: 2000
  ident: B160
  article-title: Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis
  publication-title: J. Biol. Chem
  doi: 10.1074/jbc.M001486200
– volume: 227
  start-page: 680
  year: 1970
  ident: B78
  article-title: Cleavage of structural proteins during the assembly of the head of bacteriophage T4
  publication-title: Nature
  doi: 10.1038/227680a0
– volume: 72
  start-page: 865
  year: 1986
  ident: B164
  article-title: Isolation of a neurotoxin from the salivary glands of female Rhipicephalus evertsi evertsi
  publication-title: J. Parasitol
  doi: 10.2307/3281836
– volume: 268
  start-page: 5445
  year: 1993
  ident: B173
  article-title: Isolation of an inhibitor selective for collagen-stimulated platelet aggregation from the soft tick Ornithodoros moubata
  publication-title: J. Biol. Chem
  doi: 10.1016/S0021-9258(18)53341-X
– volume: 99
  start-page: 3602
  year: 2002
  ident: B51
  article-title: Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex
  publication-title: Blood
  doi: 10.1182/blood-2001-12-0237
– volume: 117
  start-page: 120
  year: 2015
  ident: B150
  article-title: Sexual differences in the sialomes of the zebra tick, Rhipicephalus pulchellus
  publication-title: J. Proteomics
  doi: 10.1016/j.jprot.2014.12.014
– volume: 10
  start-page: 529
  year: 2019
  ident: B102
  article-title: The transcriptome of the salivary glands of Amblyomma aureolatum reveals the antimicrobial peptide microplusin as an important factor for the tick protection against Rickettsia rickettsii infection
  publication-title: Front. Physiol
  doi: 10.3389/fphys.2019.00529
– volume: 100
  start-page: 283
  ident: B96
  article-title: The sand tampan, Ornithodoros savignyi, as a model for tick–host interactions
  publication-title: S. Afr. J. Sci.
– volume: 66
  start-page: 225
  year: 2002
  ident: B79
  article-title: Isolation of Ixodes ricinus salivary gland mRNA encoding factors induced during blood feeding
  publication-title: Am. J. Trop. Med. Hyg
  doi: 10.4269/ajtmh.2002.66.225
– volume: 271
  start-page: 17785
  year: 1996
  ident: B171
  article-title: Variabilin, a novel RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis
  publication-title: J. Biol. Chem
  doi: 10.1074/jbc.271.30.17785
– volume: 9
  start-page: 233
  year: 2008
  ident: B27
  article-title: Insight into the sialome of the castor bean tick, Ixodes ricinus
  publication-title: BMC Genomics
  doi: 10.1186/1471-2164-9-233
– volume: 42
  start-page: 98
  year: 2017
  ident: B157
  article-title: Alternative splicing may not be the key to proteome complexity
  publication-title: Trends Biochem. Sci
  doi: 10.1016/j.tibs.2016.08.008
– volume: 184
  start-page: 1078
  year: 1959
  ident: B153
  article-title: New cell types in the salivary glands of the brown ear tick, Rhipicephalus appendiculatus Neumann
  publication-title: Nature
  doi: 10.1038/1841078a0
– volume: 64
  start-page: 807
  year: 2019
  ident: B119
  article-title: De novo RNA-seq and functional annotation of Haemaphysalis longicornis
  publication-title: Acta Parasitol
  doi: 10.2478/s11686-019-00103-2
– volume: 3
  start-page: 317
  year: 1983
  ident: B111
  article-title: In search of the causal agents of tick toxicoses
  publication-title: Toxicon S
  doi: 10.1016/0041-0101(83)90219-2
– volume: 250
  start-page: 4007
  year: 1975
  ident: B120
  article-title: High resolution two-dimensional electrophoresis of proteins
  publication-title: J. Biol. Chem
  doi: 10.1016/S0021-9258(19)41496-8
– volume: 4
  start-page: 469
  year: 2013
  ident: B123
  article-title: Proteome of Rhipicephalus sanguineus tick saliva induced by the secretagogues pilocarpine and dopamine
  publication-title: Ticks Tick Borne Dis
  doi: 10.1016/j.ttbdis.2013.05.001
– volume: 6
  start-page: 217
  year: 1913
  ident: B138
  article-title: The anatomy of Argas persicus (Oken 1818). part II
  publication-title: Parasitology
  doi: 10.1017/S0031182000003073
– volume: 117
  start-page: 12657
  year: 2020
  ident: B52
  article-title: Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition
  publication-title: Proc. Natl. Acad. Sci. U.S.A.
  doi: 10.1073/pnas.2000605117
– volume: 10
  start-page: 555
  year: 2020
  ident: B166
  article-title: Tick and host-derived compounds detected in the cement complex substance
  publication-title: Biomolecules
  doi: 10.3390/biom10040555
– volume: 32
  start-page: 833
  year: 2002
  ident: B16
  article-title: A cement protein of the tick Rhipicephalus appendiculatus, located in the secretory e cell granules of the type III salivary gland acini, induces strong antibody responses in cattle
  publication-title: Int. J. Parasitol
  doi: 10.1016/S0020-7519(02)00027-9
– volume: 35
  start-page: 715
  ident: B13
  article-title: Noncoding RNAs in parasite-vector-host interactions
  publication-title: Trends Parasitol
  doi: 10.1016/j.pt.2019.06.012
– volume: 139
  start-page: 45
  year: 1998
  ident: B63
  article-title: Isolation of two functional retinoid X receptor subtypes from the ixodid tick, Amblyomma americanum (L.)
  publication-title: Mol. Cell. Endocrinol
  doi: 10.1016/S0303-7207(98)00073-2
– volume: 22
  start-page: 603
  year: 1998
  ident: B68
  article-title: Cloning, nucleotide sequence and expression of the gene encoding factor Xa inhibitor from the salivary glands of the tick, Ornithodoros savignyi
  publication-title: Exp. Appl. Acarol
  doi: 10.1023/A:1006198713791
– volume: 4
  start-page: 91
  year: 1966
  ident: B69
  article-title: Isolation of tick paralysis toxin from Ixodes holocyclus
  publication-title: Toxicon
  doi: 10.1016/0041-0101(66)90003-1
– volume: 7
  start-page: 476
  year: 2017
  ident: B40
  article-title: Analysis of the salivary gland transcriptome of unfed and partially fed Amblyomma sculptum ticks and descriptive proteome of the saliva
  publication-title: Front. Cell Infect. Microbiol
  doi: 10.3389/fcimb.2017.00476
– volume: 54
  start-page: 443
  year: 1987
  ident: B114
  article-title: Biochemical studies on the salivary glands and haemolymph of Amblyomma hebraeum
  publication-title: Onderstepoort J. Vet. Res
– volume: 5
  start-page: 53
  year: 2018
  ident: B127
  article-title: Tick paralysis: solving an enigma
  publication-title: Vet. Sci
  doi: 10.3390/vetsci5020053
– volume: 43
  start-page: 99
  year: 1975
  ident: B67
  article-title: Some toxic and chemical properties of the oral secretion of the sand tampan, Ornithodoros savignyi (Audouin) (1827)
  publication-title: Onderstepoort J. Vet. Res
– volume: 25
  start-page: 269
  year: 2009
  ident: B103
  article-title: Bovine immunity - a driver for diversity in Theileria parasites?
  publication-title: Trends Parasitol
  doi: 10.1016/j.pt.2009.03.005
– volume: 37
  start-page: 48
  year: 2007
  ident: B1
  article-title: Transcriptome analysis of the salivary glands of Dermacentor andersoni Stiles (Acari: Ixodidae)
  publication-title: Insect Biochem. Mol. Biol.
  doi: 10.1016/j.ibmb.2006.10.002
– volume: 7
  start-page: 536
  year: 2016
  ident: B35
  article-title: De novo assembly and annotation of the salivary gland transcriptome of Rhipicephalus appendiculatus male and female ticks during blood feeding
  publication-title: Ticks Tick Borne Dis
  doi: 10.1016/j.ttbdis.2016.01.014
– volume: 74
  start-page: 2892
  year: 2011
  ident: B45
  article-title: An insight into the sialotranscriptome and proteome of the coarse bontlegged tick, Hyalomma marginatum rufipes
  publication-title: J. Proteomics
  doi: 10.1016/j.jprot.2011.07.015
– volume: 34
  start-page: 1
  ident: B97
  article-title: Adaptation of ticks to a blood-feeding environment: evolution from a functional perspective
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/j.ibmb.2003.09.002
– volume: 93
  start-page: 82
  year: 1999
  ident: B117
  article-title: Savignin, a potent thrombin inhibitor isolated from the salivary glands of the tick, Ornithodoros savignyi (Acari: Argasidae)
  publication-title: Exp. Parasitol
  doi: 10.1006/expr.1999.4448
– volume: 9
  start-page: 4638
  year: 2018
  ident: B22
  article-title: A deadly dance: the choreography of host-pathogen interactions, as revealed by single-cell technologies
  publication-title: Nat. Commun
  doi: 10.1038/s41467-018-06214-0
– volume: 11
  start-page: 314
  year: 2018
  ident: B14
  article-title: De novo assembly and annotation of Hyalomma dromedarii tick (Acari: Ixodidae) sialotranscriptome with regard to gender differences in gene expression
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-018-2874-9
– volume: 33
  start-page: 489
  year: 2009
  ident: B19
  article-title: IrAM-An alpha2-macroglobulin from the hard tick Ixodes ricinus: characterization and function in phagocytosis of a potential pathogen Chryseobacterium indologenes
  publication-title: Dev. Comp. Immunol
  doi: 10.1016/j.dci.2008.09.011
– volume: 78
  start-page: 443
  year: 2019
  ident: B44
  article-title: Proteomic analysis of saliva from partially and fully engorged adult female Rhipicephalus microplus (Acari: Ixodidae)
  publication-title: Exp. Appl. Acarol
  doi: 10.1007/s10493-019-00390-4
– volume: 107
  start-page: 5
  year: 2020
  ident: B129
  article-title: Paleoproteomics explained to youngsters: how did the wedding of two-dimensional electrophoresis and protein sequencing spark proteomics on: let there be light
  publication-title: J. Proteomics
  doi: 10.1016/j.jprot.2014.03.011
– volume: 32
  start-page: 1101
  ident: B162
  article-title: Toward a description of the sialome of the adult female mosquito Aedes aegypti
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/S0965-1748(02)00047-4
– volume: 12
  start-page: 613
  year: 2019
  ident: B131
  article-title: Salivary gland proteome analysis of developing adult female Haemaphysalis longicornis ticks: molecular motor and TCA cycle-related proteins play an important role throughout development
  publication-title: Parasit. Vectors
  doi: 10.1186/s13071-019-3864-2
– volume: 40
  start-page: 890
  year: 2003
  ident: B175
  article-title: Cloning and sequencing of putative acetylcholinesterase cDNAs from the American dog tick, Dermacentor variabilis, and the brown dog tick, Rhipicephalus sanguineus (Acari: Ixodidae)
  publication-title: J. Med. Entomol
  doi: 10.1603/0022-2585-40.6.890
– volume: 22
  start-page: 142
  year: 1969
  ident: B113
  article-title: Purification of the toxic component in the oral secretion of the sand tampan Ornithodoros savignyi (Audouin) (1827)
  publication-title: J. S. Afr. Chem. Ind
– volume: 15
  start-page: 518
  year: 2014
  ident: B130
  article-title: A 24-48 h fed Amblyomma americanum tick saliva immuno-proteome
  publication-title: BMC Genomics
  doi: 10.1186/1471-2164-15-518
– volume: 14
  start-page: e0007758
  year: 2020
  ident: B75
  article-title: Time-resolved proteomic profile of Amblyomma americanum tick saliva during feeding
  publication-title: PLoS Negl. Trop. Dis
  doi: 10.1371/journal.pntd.0007758
– volume: 53
  start-page: 147
  year: 2011
  ident: B121
  article-title: Multiple transcripts encode glucose 6-phosphate dehydrogenase in the southern cattle tick, Rhipicephalus (Boophilus) microplus
  publication-title: Exp. Appl. Acarol
  doi: 10.1007/s10493-010-9392-6
– volume: 59
  start-page: 339
  year: 2013
  ident: B177
  article-title: Distinctive microRNA profiles in the salivary glands of Haemaphysalis longicornis related to tick blood-feeding
  publication-title: Exp. Appl. Acarol
  doi: 10.1007/s10493-012-9604-3
– volume: 28
  start-page: 77
  year: 2002
  ident: B86
  article-title: A proteomics approach to characterizing tick salivary secretions
  publication-title: Exp. Appl. Acarol
  doi: 10.1023/A:1025342015065
– volume: 8
  start-page: 161
  year: 1972
  ident: B8
  article-title: Bloodsucking ticks (Ixodideae)—vectors of disease of man and animals
  publication-title: Misc. Pub. Entomol. Soc. Amer
– volume: 6
  start-page: e28525
  year: 2011
  ident: B72
  article-title: A deep insight into the sialotranscriptome of the Gulf Coast tick, Amblyomma maculatum
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0028525
– volume: 109
  start-page: 517
  year: 1994
  ident: B170
  article-title: Comparison of the proteins in salivary glands, saliva and haemolymph of Rhipicephalus appendiculatus female ticks during feeding
  publication-title: Parasitology
  doi: 10.1017/S003118200008077X
– volume: 33
  start-page: 267
  year: 2003
  ident: B108
  article-title: Four serine proteinase inhibitors (serpin) from the brown ear tick, Rhiphicephalus appendiculatus; cDNA cloning and preliminary characterization
  publication-title: Insect Biochem. Mol. Biol
  doi: 10.1016/S0965-1748(02)00240-0
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Snippet Species have definitive genomes. Even so, the transcriptional and translational products of the genome are dynamic and subject to change over time. This is...
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SubjectTerms Cellular and Infection Microbiology
proteome
salivary gland
sialome
sialoverse
tick
transcriptome
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Title Quantitative Visions of Reality at the Tick-Host Interface: Biochemistry, Genomics, Proteomics, and Transcriptomics as Measures of Complete Inventories of the Tick Sialoverse
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Volume 10
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