Serum BDNF as a Potential Biomarker of Alzheimer's Disease: Verification Through Assessment of Serum, Cerebrospinal Fluid, and Medial Temporal Lobe Atrophy

• Published in: Frontiers in neurology Vol. 12; p. 653267
• Main Authors: Mori, Yukiko, Tsuji, Mayumi, Oguchi, Tatsunori, Kasuga, Kensaku, Kimura, Atsushi, Futamura, Akinori, Sugimoto, Azusa, Kasai, Hideyo, Kuroda, Takeshi, Yano, Satoshi, Hieda, Sotaro, Kiuchi, Yuji, Ikeuchi, Takeshi, Ono, Kenjiro
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 23.04.2021
• Subjects: Alzheimer's disease; BDNF; blood biomarker; medial temporal lobe atrophy; mild cognitive impairment; Neurology; mild cognitive impairment; blood biomarker; BDNF; Alzheimer's disease; medial temporal lobe atrophy

There is an urgent need to establish blood biomarkers for Alzheimer's disease (AD). Although it has been speculated that brain-derived neurotrophic factor (BDNF) is associated with AD, whether it can be used as a blood biomarker has yet to be determined. We used serum, cerebrospinal fluid (CSF)...