Using Live-Cell Imaging and Synthetic Biology to Probe Directed Migration in Dictyostelium

• Published in: Frontiers in cell and developmental biology Vol. 9; p. 740205
• Main Authors: Kuhn, Jonathan, Lin, Yiyan, Devreotes, Peter N.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 05.10.2021
• Subjects: Cell and Developmental Biology; chemotaxis; imaging; migration; signaling; synthetic & systems biology; migration; synthetic & systems biology; signaling; imaging; chemotaxis

For decades, the social amoeba Dictyostelium discoideum has been an invaluable tool for dissecting the biology of eukaryotic cells. Its short growth cycle and genetic tractability make it ideal for a variety of biochemical, cell biological, and biophysical assays. Dictyostelium have been widely used...