Transcriptional and Epigenomic Regulation of Adipogenesis

• Published in: Molecular and cellular biology Vol. 39; no. 11
• Main Authors: Lee, Ji-Eun, Schmidt, Hannah, Lai, Binbin, Ge, Kai
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.06.2019; American Society for Microbiology
• Subjects: acetylation; adipocytes; Adipogenesis; Animals; cell culture; Cell Differentiation; chromatin; demethylation; DNA methylation; epigenome; epigenomic regulation; Epigenomics - methods; Gene Expression Profiling - methods; Gene Expression Regulation; histones; Humans; microRNA; Minireview; obesity; peroxisome proliferator-activated receptor gamma; transcription (genetics); transcriptional regulation; epigenomic regulation; transcriptional regulation; adipogenesis

Understanding adipogenesis, the process of adipocyte development, may provide new ways to treat obesity and related metabolic diseases. Adipogenesis is controlled by coordinated actions of lineage-determining transcription factors and epigenomic regulators. Peroxisome proliferator-activated receptor...