Microbiota perturbation by anti-microbiota vaccine reduces the colonization of Borrelia afzelii in Ixodes ricinus

• Published in: Microbiome Vol. 11; no. 1; pp. 151 - 21
• Main Authors: Wu-Chuang, Alejandra, Mateos-Hernandez, Lourdes, Maitre, Apolline, Rego, Ryan O. M., Šíma, Radek, Porcelli, Stefania, Rakotobe, Sabine, Foucault-Simonin, Angélique, Moutailler, Sara, Palinauskas, Vaidas, Aželytė, Justė, Sǐmo, Ladislav, Obregon, Dasiel, Cabezas-Cruz, Alejandro
• Format: Journal Article
• Language: English
• Published: England BioMed Central 24.07.2023; BMC
• Subjects: Animals; Anti-microbiota vaccine; Antibiotics; Antibodies; Arachnids; Bacteria; Bacterial proteins; Borrelia; Borrelia afzelii; Borrelia burgdorferi Group; Borrelia burgdorferi Group - physiology; Borreliosis; E coli; Europe; Immunization; Infections; Ixodes; Ixodes - microbiology; Ixodes - physiology; Ixodes ricinus; Life Sciences; Lyme borreliosis; Lyme Disease; Lyme Disease - microbiology; Medical importance; Microbiota; Pathogens; Spirochetes; Vaccines; Vector microbiota; Europe; St Louis Missouri; France; United States > US; Lyme borreliosis; Borrelia afzelii; Ixodes ricinus; Vector microbiota; Anti-microbiota vaccine

Ticks can transmit a broad variety of pathogens of medical importance, including Borrelia afzelii, the causative agent of Lyme borreliosis in Europe. Tick microbiota is an important factor modulating, not only vector physiology, but also the vector competence. Anti-microbiota vaccines targeting keys...