Toll-like Receptor 7 and TLR9 Dictate Autoantibody Specificity and Have Opposing Inflammatory and Regulatory Roles in a Murine Model of Lupus - Christensen, Sean R.; Shupe, Jonathan; Nickerson, Kevin; Kashgarian, Michael; Flavell, Richard A.; Shlomchik, Mark J. (Immunity (Cambridge, Mass.), 2006)
Keywords: Animals; Antibody Specificity; Autoantibodies - biosynthesis; Autoimmune diseases; CELLIMMUNO; Cells, Cultured; Deoxyribonucleic acid; Dilution; DNA; Female; Humans; HUMDISEASE; Immune system; Immunoglobulin G - blood; Lupus; Lupus Erythematosus, Systemic - immunology; Lupus Erythematosus, Systemic - metabolism; Lupus Erythematosus, Systemic - pathology; Lymphocyte Activation - immunology; Male; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, Knockout; MOLIMMUNO; Mortality; Rodents; Studies; Toll-Like Receptor 7 - deficiency; Toll-Like Receptor 7 - genetics; Toll-Like Receptor 7 - physiology; Toll-Like Receptor 9 - deficiency; Toll-Like Receptor 9 - genetics; Toll-Like Receptor 9 - physiology; MOLIMMUNO; HUMDISEASE; CELLIMMUNO