The tissue-engineered vascular graft using bone marrow without culture

• Published in: The Journal of thoracic and cardiovascular surgery Vol. 129; no. 5; pp. 1064 - 1070
• Main Authors: Hibino, Narutoshi, Shin’oka, Toshiharu, Matsumura, Goki, Ikada, Yoshihito, Kurosawa, Hiromi
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Mosby, Inc 01.05.2005; AATS/WTSA; Elsevier
• Subjects: Animals; Biological and medical sciences; Bioprosthesis - standards; Blood Vessel Prosthesis - standards; Blood Vessel Prosthesis Implantation - methods; Bone Marrow Cells - physiology; Bone Marrow Cells - ultrastructure; Bone Marrow Transplantation - methods; Calcium - analysis; Caproates - chemistry; Caproates - therapeutic use; Cell Culture Techniques - methods; Collagen Type IV - analysis; Collagen Type IV - biosynthesis; DNA - analysis; Dogs; Femoral Vein - cytology; Hydroxyproline - analysis; Immunohistochemistry; Lactic Acid - chemistry; Lactic Acid - therapeutic use; Lactones - chemistry; Lactones - therapeutic use; Medical sciences; Microscopy, Electron; Models, Animal; Platelet Endothelial Cell Adhesion Molecule-1 - analysis; Polyesters; Polyglycolic Acid - chemistry; Polyglycolic Acid - therapeutic use; Polymers - chemistry; Polymers - therapeutic use; Random Allocation; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Tissue and Organ Procurement - methods; Tissue Engineering - methods; Transplantation, Autologous - methods; Vena Cava, Inferior - surgery; Heart; Cell culture; Treatment; Surgery; Blood vessel; Tissue culture; Bone marrow; Thorax

To overcome the shortcomings of current vascular grafts, tissue-engineering methods have been applied to cardiovascular regions. We previously reported the creation of a tissue-engineered vascular graft by using vascular mixed cells. However, the cost and manpower for harvesting and culturing the ce...