Epigenetic transmission of feline infectious peritonitis

Feline Infectious Peritonitis (F.I.P.) was diagnosed in the kittens of two successive litters born to a female presumed also infected. At the same time, the two fathers and the other subjects of the cattery remained asymptomatic of F.I.P. The clinical observations, supported by electrophoretic data,...

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Published inComparative immunology, microbiology and infectious diseases Vol. 1; no. 1; pp. 67 - 70
Main Authors Pastoret, P.-P, Henroteaux, M
Format Journal Article Web Resource
LanguageEnglish
Published England Elsevier Ltd 1978
Elsevier Science
Published by Elsevier Ltd
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ISSN0147-9571
1878-1667
DOI10.1016/0147-9571(78)90012-7

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Abstract Feline Infectious Peritonitis (F.I.P.) was diagnosed in the kittens of two successive litters born to a female presumed also infected. At the same time, the two fathers and the other subjects of the cattery remained asymptomatic of F.I.P. The clinical observations, supported by electrophoretic data, suggest the possibility of a direct transmission of the disease by the mother to her offspring, either by the transplacentary pathway (epigenetic transmission) or via the milk. La péritonite infectieuse féline a été diagnostiquée chez les chatons de deux portées successives issues d'une mère elle-mm̂e présumée atteinte. Dans le même temps, les deux pères et les autres sujets de l'élevage sont restés indemnes de tout symptôme de péritonite infectieuse. Les observations cliniques étayées par des données électrophorétiques, suggèrent dans ce cas, la possibilité d'une transmission directe de la maladie par la mère à ses petits, soit par la voie transplacentaire (transmission épigénétique), soit par le lait. La voie naturelle d'infection de la péritonite infectieuse reste encore mal connue et controversée; ceci d'autant plus que certaines caractéristiques du virus laissent à penser qu'il ne peut résister très longtemps dans le milieu extérieur; et que, d'autre part, les études expérimentales ont montré la difficulté de transmettre la maladie par les voies naturelles. Par contre, les voies d'inoculation sous-cutanée, intraveineuse et intrapéritonéale sont généralement suivies de succès. Dans l'état actuel de nos connaissances, la transmission épigénétique de la maladie paraît constituer une des voies que peut emprunter le virus pour se propager.
AbstractList Feline Infectious Peritonitis (F.I.P.) was diagnosed in the kittens of two successive litters born to a female presumed also infected. At the same time, the two fathers and the other subjects of the cattery remained asymptomatic of F.I.P. The clinical observations, supported by electrophoretic data, suggest the possibility of a direct transmission of the disease by the mother to her offspring, either by the transplacentary pathway (epigenetic transmission) or via the milk.
Feline Infectious Peritonitis (F.I.P.) was diagnosed in the kittens of two successive litters born to a female presumed also infected. At the same time, the two fathers and the other subjects of the cattery remained asymptomatic of F.I.P. The clinical observations, supported by electrophoretic data, suggest the possibility of a direct transmission of the disease by the mother to her offspring, either by the transplacentary pathway (epigenetic transmission) or via the milk. © 1978.
Feline Infectious Peritonitis (F.I.P.) was diagnosed in the kittens of two successive litters born to a female presumed also infected. At the same time, the two fathers and the other subjects of the cattery remained asymptomatic of F.I.P. The clinical observations, supported by electrophoretic data, suggest the possibility of a direct transmission of the disease by the mother to her offspring, either by the transplacentary pathway (epigenetic transmission) or via the milk. La péritonite infectieuse féline a été diagnostiquée chez les chatons de deux portées successives issues d'une mère elle-mm̂e présumée atteinte. Dans le même temps, les deux pères et les autres sujets de l'élevage sont restés indemnes de tout symptôme de péritonite infectieuse. Les observations cliniques étayées par des données électrophorétiques, suggèrent dans ce cas, la possibilité d'une transmission directe de la maladie par la mère à ses petits, soit par la voie transplacentaire (transmission épigénétique), soit par le lait. La voie naturelle d'infection de la péritonite infectieuse reste encore mal connue et controversée; ceci d'autant plus que certaines caractéristiques du virus laissent à penser qu'il ne peut résister très longtemps dans le milieu extérieur; et que, d'autre part, les études expérimentales ont montré la difficulté de transmettre la maladie par les voies naturelles. Par contre, les voies d'inoculation sous-cutanée, intraveineuse et intrapéritonéale sont généralement suivies de succès. Dans l'état actuel de nos connaissances, la transmission épigénétique de la maladie paraît constituer une des voies que peut emprunter le virus pour se propager.
Author Henroteaux, M
Pastoret, P.-P
AuthorAffiliation b Clinique médicale des petits animaux Faculté de Médecine vétérinaire U.Lg., 45, rue des Vétérinaires, 1070 Bruxelles, Belgium
a Laboratoire de Virologie, 45, rue des Vétérinaires, 1070 Bruxelles, Belgium
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Cites_doi 10.1016/0042-6822(70)90070-X
10.1177/0300985875012005-00601
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Issue 1
Keywords feline infectious peritonitis (FIP)
epidemiology
peritonite infectieuse féline (PIF)
Epigenetic transmission
Transmission épigénétique
coronavirus
epidémiologie
Language English
License https://www.elsevier.com/tdm/userlicense/1.0
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Potkay, Bacher, Pitts (BIB9) 1974; 24
Pedersen (BIB5) 1976; 37
Pedersen (BIB7) 1976; 6
Norsworthy (BIB10) 1974; 4
Osterhaus, Horzinek, Ellens (BIB3) 1976; 89
Ward (BIB2) 1970; 41
Starks, Corstvet, Buckner (BIB4) 1976; 37
Pedersen (BIB6) 1976; 37
Gouffaux, Pastoret, Henroteaux, Massip (BIB12) 1975; 12
Zook, King, Robison, McCombs (BIB1) 1968; 5
Cotter, Gilmore, Rollins (BIB8) 1973; 162
Ward (10.1016/0147-9571(78)90012-7_BIB2) 1970; 41
Cotter (10.1016/0147-9571(78)90012-7_BIB8) 1973; 162
Norsworthy (10.1016/0147-9571(78)90012-7_BIB10) 1974; 4
Pedersen (10.1016/0147-9571(78)90012-7_BIB7) 1976; 6
Potkay (10.1016/0147-9571(78)90012-7_BIB9) 1974; 24
Pedersen (10.1016/0147-9571(78)90012-7_BIB6) 1976; 37
Zook (10.1016/0147-9571(78)90012-7_BIB1) 1968; 5
Osterhaus (10.1016/0147-9571(78)90012-7_BIB3) 1976; 89
Pedersen (10.1016/0147-9571(78)90012-7_BIB5) 1976; 37
Starks (10.1016/0147-9571(78)90012-7_BIB4) 1976; 37
Pastoret (10.1016/0147-9571(78)90012-7_BIB11) 1974; 118
Gouffaux (10.1016/0147-9571(78)90012-7_BIB12) 1975; 12
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  article-title: Untersuchungen zur ätiologie der felinen infektiösen peritonitis
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– volume: 4
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  year: 1974
  ident: 10.1016/0147-9571(78)90012-7_BIB10
  article-title: Neonatal feline infectious peritonitis
  publication-title: Feline Practice
– volume: 37
  start-page: 335
  year: 1976
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  publication-title: Am. J. vet. Res.
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  start-page: 191
  year: 1970
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  start-page: 335
  year: 1975
  ident: 10.1016/0147-9571(78)90012-7_BIB12
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  start-page: 279
  year: 1974
  ident: 10.1016/0147-9571(78)90012-7_BIB9
  article-title: Feline Infectious Peritonitis in a closed breeding colony
  publication-title: Lab. Anim. Sci.
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  start-page: 567
  year: 1976
  ident: 10.1016/0147-9571(78)90012-7_BIB5
  article-title: Morphologic and physical characteristics of feline infectious peritonitis virus and its growth in autochtonous peritoneal cells cultures
  publication-title: Am. J. vet. Res.
– volume: 37
  start-page: 1449
  year: 1976
  ident: 10.1016/0147-9571(78)90012-7_BIB6
  article-title: Serologic studies of naturally occurring feline infectious peritonitis
  publication-title: Am. J. vet. Res.
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  start-page: 91
  year: 1968
  ident: 10.1016/0147-9571(78)90012-7_BIB1
  article-title: Ultrastructural evidence for the viral etiology of feline infectious peritonitis
  publication-title: Path. Vet.
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  start-page: 42
  year: 1976
  ident: 10.1016/0147-9571(78)90012-7_BIB7
  article-title: Feline infectious peritonitis: something old, something new
  publication-title: Feline Practice
– volume: 162
  start-page: 1054
  year: 1973
  ident: 10.1016/0147-9571(78)90012-7_BIB8
  article-title: Multiple cases of Feline Leukemia and Feline Infectious Peritonitis in a household
  publication-title: J. Am. vet. med. Ass.
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Snippet Feline Infectious Peritonitis (F.I.P.) was diagnosed in the kittens of two successive litters born to a female presumed also infected. At the same time, the...
Feline Infectious Peritonitis (F.I.P.) was diagnosed in the kittens of two successive litters born to a female presumed also infected. At the same time, the...
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SubjectTerms Animal
animal diseases
animal health
Animals
Cats
coronavirus
epidemiology
epidémiologie
Epigenetic transmission
feline infectious peritonitis (FIP)
Female
Fibrinogen
Gamma-Globulins
Glycoproteins
Haptoglobins
Life sciences
Male
Médecine vétérinaire & santé animale
peritonite infectieuse féline (PIF)
Peritonitis
Peritonitis - transmission
Sciences du vivant
Serum Albumin
Transferrin
Transmission épigénétique
Veterinary medicine & animal health
Title Epigenetic transmission of feline infectious peritonitis
URI https://dx.doi.org/10.1016/0147-9571(78)90012-7
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