Endocrinopathies in Inborn Errors of Immunity

• Published in: Frontiers in immunology Vol. 12; p. 786241
• Main Authors: Takasawa, Kei, Kanegane, Hirokazu, Kashimada, Kenichi, Morio, Tomohiro
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 23.11.2021
• Subjects: Animals; Autoimmunity - genetics; diabetes mellitus; Disease Models, Animal; Endocrine System Diseases - chemically induced; Endocrine System Diseases - genetics; Endocrine System Diseases - immunology; endocrinopathy; Glucocorticoids - administration & dosage; Glucocorticoids - adverse effects; growth failure; HCT; Hematopoietic Stem Cell Transplantation - adverse effects; Humans; Immunology; inborn errors of immunity (IEIs); Primary Immunodeficiency Diseases - complications; Primary Immunodeficiency Diseases - genetics; Primary Immunodeficiency Diseases - immunology; Primary Immunodeficiency Diseases - therapy; thyroiditis; HCT; growth failure; inborn errors of immunity (IEIs); diabetes mellitus; thyroiditis; endocrinopathy

Inborn errors of immunity (IEI), caused by hereditary or genetic defects, are a group of more than 400 disorders, in which the immune system, including lymphocytes, neutrophils, macrophages, and complements, does not function properly. The endocrine system is frequently affected by IEI as an associa...