Occupational Benzene Exposure and Lung Cancer Risk: A Pooled Analysis of 14 Case-Control Studies

• Published in: American journal of respiratory and critical care medicine Vol. 209; no. 2; pp. 185 - 196
• Main Authors: Wan, Wenxin, Peters, Susan, Portengen, Lützen, Olsson, Ann, Schüz, Joachim, Ahrens, Wolfgang, Schejbalova, Miriam, Boffetta, Paolo, Behrens, Thomas, Brüning, Thomas, Kendzia, Benjamin, Consonni, Dario, Demers, Paul A., Fabiánová, Eleonóra, Fernández-Tardón, Guillermo, Field, John K., Forastiere, Francesco, Foretova, Lenka, Guénel, Pascal, Gustavsson, Per, Jöckel, Karl-Heinz, Karrasch, Stefan, Landi, Maria Teresa, Lissowska, Jolanta, Barul, Christine, Mates, Dana, McLaughlin, John R., Merletti, Franco, Migliore, Enrica, Richiardi, Lorenzo, Pándics, Tamás, Pohlabeln, Hermann, Siemiatycki, Jack, Świątkowska, Beata, Wichmann, Heinz-Erich, Zaridze, David, Ge, Calvin, Straif, Kurt, Kromhout, Hans, Vermeulen, Roel
• Format: Journal Article
• Language: English
• Published: United States American Thoracic Society 15.01.2024
• Subjects: Benzene - toxicity; Cancer; Carcinogens; Case-Control Studies; Human exposure; Humans; Hydrocarbons; Life Sciences; Lung; Lung cancer; Lung Neoplasms - chemically induced; Lung Neoplasms - epidemiology; Occupational Diseases - chemically induced; Occupational Diseases - epidemiology; Occupational Exposure - adverse effects; Occupational health; Original; Risk factors; lung cancer; occupational exposure; benzene

Benzene has been classified as carcinogenic to humans, but there is limited evidence linking benzene exposure to lung cancer. We aimed to examine the relationship between occupational benzene exposure and lung cancer. Subjects from 14 case-control studies across Europe and Canada were pooled. We use...