Phosphorus and Risk of Renal Failure in Subjects with Normal Renal Function

• Published in: The American journal of medicine Vol. 126; no. 4; pp. 311 - 318
• Main Authors: Sim, John J., Bhandari, Simran K., Smith, Ning, Chung, Joanie, Liu, In Lu A., Jacobsen, Steven J., Kalantar-Zadeh, Kamyar
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2013; Elsevier Sequoia S.A
• Subjects: Adult; Age; Aged; Analysis of Variance; Clinical outcomes; Cohort Studies; Diabetes mellitus; End-stage renal disease risk; Epidemiology; Ethnic groups; Female; Glomerular Filtration Rate; Humans; Hypertension; Internal Medicine; Kidney; Kidney - metabolism; Kidney diseases; Kidney Failure, Chronic - blood; Kidney Failure, Chronic - epidemiology; Kidney Failure, Chronic - mortality; Male; Middle Aged; Mortality; Outcomes; Phosphorus; Phosphorus - blood; Proportional Hazards Models; Regression Analysis; Renal; Renal function; Retrospective Studies; Risk Factors; Phosphorus; End-stage renal disease risk; Epidemiology; Outcomes

Whether higher serum phosphorus levels increase risk for kidney disease onset and progression to end-stage renal disease in those with normal renal function is largely unknown. We sought to determine whether higher serum phosphorus levels increase risk for end-stage renal disease within a large ethn...