Etiopathogenesis of acquired cholesteatoma: prominent theories and recent advances in biomolecular research

• Published in: The Laryngoscope Vol. 125; no. 1; p. 234
• Main Author: Kuo, Chin-Lung
• Format: Journal Article
• Language: English
• Published: United States 01.01.2015
• Subjects: Cell Movement - physiology; Cell Proliferation - physiology; Cholesteatoma, Middle Ear - etiology; Cholesteatoma, Middle Ear - genetics; Cholesteatoma, Middle Ear - pathology; Cholesteatoma, Middle Ear - physiopathology; Ear, Middle - pathology; Ear, Middle - physiopathology; Epigenesis, Genetic - genetics; Epigenesis, Genetic - physiology; Epithelium - pathology; Epithelium - physiopathology; Eustachian Tube - pathology; Eustachian Tube - physiopathology; Genomic Instability - genetics; Genomic Instability - physiology; Humans; Hyperplasia - pathology; Hyperplasia - physiopathology; Intercellular Signaling Peptides and Proteins - genetics; Intercellular Signaling Peptides and Proteins - physiology; Mastoid - pathology; Mastoid - physiopathology; Metaplasia - pathology; Metaplasia - physiopathology; Otitis Media - pathology; Otitis Media - physiopathology; Pulmonary Ventilation - physiology; Connexin 26; pathogenesis; microRNA; cytokines; etiology

To review recent biomolecular advances in etiopathogenesis of acquired cholesteatoma. MEDLINE via OVID (to March 2014) and PubMed (to March 2014). All articles referring to etiopathogenesis of acquired cholesteatoma were identified in the above databases, from which 89 articles were included in this...