Specific Aquaporins Facilitate the Diffusion of Hydrogen Peroxide across Membranes

• Published in: The Journal of biological chemistry Vol. 282; no. 2; pp. 1183 - 1192
• Main Authors: Bienert, Gerd P., Møller, Anders L.B., Kristiansen, Kim A., Schulz, Alexander, Møller, Ian M., Schjoerring, Jan K., Jahn, Thomas P.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 12.01.2007; American Society for Biochemistry and Molecular Biology
• Subjects: Animals; Aquaporin 1 - genetics; Aquaporin 1 - metabolism; Aquaporin 2 - genetics; Aquaporin 2 - metabolism; Aquaporin 3 - genetics; Aquaporin 3 - metabolism; Aquaporin 4 - genetics; Aquaporin 4 - metabolism; Aquaporin 5 - genetics; Aquaporin 5 - metabolism; Aquaporins - genetics; Aquaporins - metabolism; Arabidopsis; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Catalase - metabolism; Cell Membrane - metabolism; Diffusion; Gene Expression; Humans; Hydrogen Peroxide - pharmacokinetics; Microscopy, Confocal; Osmosis - physiology; Rats; Saccharomyces cerevisiae - genetics; Saccharomyces cerevisiae - metabolism; Silver - pharmacology; Spheroplasts - metabolism; Transformation, Genetic; Water - metabolism

The metabolism of aerobic organisms continuously produces reactive oxygen species. Although potentially toxic, these compounds also function in signaling. One important feature of signaling compounds is their ability to move between different compartments, e.g. to cross membranes. Here we present ev...