The current role of dendritic cells in the progression and treatment of colorectal cancer

• Published in: Cancer biology & medicine Vol. 21; no. 9; pp. 1 - 15
• Main Authors: Zhang, Yuanci, Ji, Songtao, Miao, Ge, Du, Shuya, Wang, Haojia, Yang, Xiaohua, Li, Ang, Lu, Yuanyuan, Wang, Xin, Zhao, Xiaodi
• Format: Journal Article
• Language: English
• Published: China State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,National Clinical Research Center for Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China 22.08.2024; Department of Experimental Surgery,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China%State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,National Clinical Research Center for Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China; Department of Gastroenterology,the 988th Hospital of PLA Joint Logistics Support Force,Zhengzhou 450042,China%Department of Gastroenterology,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China; Department of Gastroenterology,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038,China%State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,National Clinical Research Center for Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China%State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers,National Clinical Research Center for Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China; Compuscript; China Anti-Cancer Association
• Subjects: Animals; colorectal cancer; Colorectal Neoplasms - immunology; Colorectal Neoplasms - pathology; Colorectal Neoplasms - therapy; dendritic cells; Dendritic Cells - immunology; Disease Progression; Humans; Immune Tolerance; Immunotherapy - methods; Review; treatment strategies; Tumor Microenvironment - immunology; tumor progression; treatment strategies; dendritic cells; tumor progression; Colorectal cancer

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths worldwide. Dendritic cells (DCs) constitute a heterogeneous group of antigen-presenting cells that are important for initiating and regulating both innate and adaptive immune responses. As a...