The landscape of human STR variation

• Published in: Genome research Vol. 24; no. 11; pp. 1894 - 1904
• Main Authors: Willems, Thomas, Gymrek, Melissa, Highnam, Gareth, Mittelman, David, Erlich, Yaniv
• Format: Journal Article
• Language: English
• Published: United States Cold Spring Harbor Laboratory Press 01.11.2014
• Subjects: Alleles; Gene Frequency; Genetic Variation; Genetics, Population - methods; Genome, Human - genetics; Genomics - methods; Genotype; Humans; Linkage Disequilibrium; Microsatellite Repeats - genetics; Polymorphism, Single Nucleotide; Resource

Short tandem repeats are among the most polymorphic loci in the human genome. These loci play a role in the etiology of a range of genetic diseases and have been frequently utilized in forensics, population genetics, and genetic genealogy. Despite this plethora of applications, little is known about...