Genetic Determinants of Virulence between Two Foot-and-Mouth Disease Virus Isolates Which Caused Outbreaks of Differing Severity - Nishi, Tatsuya; Morioka, Kazuki; Saito, Nobuko; Yamakawa, Makoto; Kanno, Toru; Fukai, Katsuhiko (mSphere, 2019)
Keywords: Amino acids; Animals; Animals, Suckling; Antiviral agents; Bovidae; Capsid Proteins - chemistry; Capsid Proteins - genetics; Cattle; Cell culture; Cell Line; Cell lines; Cloning; Disease Outbreaks; DNA-directed RNA polymerase; Fever; Fidelity; Foot & mouth disease; Foot-and-Mouth Disease - mortality; Foot-and-Mouth Disease - virology; foot-and-mouth disease virus; Foot-and-Mouth Disease Virus - genetics; Foot-and-Mouth Disease Virus - pathogenicity; Genes; genetic determinants; Genomes; Infections; Infectivity; Mice; Molecular Biology and Physiology; Molecular modelling; Mortality; Mutation; Outbreaks; Pathogenicity; Recombinants; Replication; RNA, Viral - genetics; RNA-directed RNA polymerase; Serotypes; Signs; Strains (organisms); Studies; Suckling behavior; Tissue culture; Virulence; Virulence Factors - genetics; Viruses; VP1 protein; Japan; virulence; foot-and-mouth disease virus; genetic determinants