Information theory based approaches to cellular signaling

• Published in: Biochimica et biophysica acta Vol. 1810; no. 10; pp. 924 - 932
• Main Authors: Waltermann, Christian, Klipp, Edda
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2011
• Subjects: Animals; biology; entropy; Humans; Information Theory; microorganisms; Models, Theoretical; molecular biology; Mutual information; neurophysiology; nutrient content; osmolarity; Sensitivity analysis; Shannon entropy; Signal integration; signal transduction; Signal Transduction - physiology; Signaling pathway; Systems biology; temperature; Shannon entropy; Sensitivity analysis; Signaling pathway; Systems biology; Signal integration; Mutual information

Cells interact with their environment and they have to react adequately to internal and external changes such changes in nutrient composition, physical properties like temperature or osmolarity and other stresses. More specifically, they must be able to evaluate whether the external change is signif...