Novel insights into the complex interplay of immune dysregulation and inflammatory biomarkers in preeclampsia and fetal growth restriction: A two-step Mendelian randomization analysis

• Published in: Journal of translational autoimmunity (Online) Vol. 8; p. 100226
• Main Authors: Zeng, Chumei, Liu, Huiying, Wang, Zilian, Li, Jingting
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2024; Elsevier
• Subjects: Fetal growth restriction; Immune dysregulation; Inflammatory factors; Mendelian randomization analysis; Preeclampsia; Research paper; Inflammatory factors; Mendelian randomization analysis; Immune dysregulation; Preeclampsia; Fetal growth restriction

The relationship between genetic immune dysregulation and the occurrence of preeclampsia (PE) or PE with fetal growth restriction (PE with FGR) has yielded inconsistent findings, and the underlying mediators of this association remain elusive. We aimed to explore the causal impact of genetic immune...