Pathogenesis of Higher Blood Pressure and Worse Renal Function in Salt-Sensitive Hypertension

• Published in: Kidney & blood pressure research Vol. 46; no. 2; pp. 236 - 244
• Main Authors: Chu, Yuguang, Zhou, Yan, Lu, Shihua, Lu, Feng, Hu, Yuanhui
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.04.2021; Karger Publishers
• Subjects: 1-Phosphatidylinositol 3-kinase; AKT protein; ambulatory blood pressure; Blood pressure; Cell proliferation; Damage; Glomerular filtration rate; growth factor; Growth factors; Health care; Hospitals; Hypertension; Immune system; Insulin-like growth factor-binding protein 2; Insulin-like growth factor-binding protein 3; Insulin-like growth factor-binding protein 6; Lymphatic system; Medical research; Mortality; Neurotrophin 4; Pathogenesis; Patients; pi3k-akt signaling pathway; Platelet-derived growth factor; Population; Proteins; renal damage; Renal function; Research Article; Salt; salt-sensitive hypertension; Salts; Software; Statistical analysis; Traditional Chinese medicine; Vascular endothelial growth factor; Vascular endothelial growth factor receptors; Water circulation; China; Ambulatory blood pressure; Salt-sensitive hypertension; Renal damage; PI3K-AKT signaling pathway; Growth factor
• ISSN: 1420-4096; 1423-0143; 1423-0143
• DOI: 10.1159/000515088

Background: The underlying pathogenesis of patients with salt-sensitive hypertension expressing higher blood pressure and severer renal damage remains uncertain. Methods: We recruited 329 subjects, 131 in salt-sensitive (SS) group, 148 in nonsalt-sensitive (NSS) group, and 50 healthy people in norma...