NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes - Chen, Yng-Tay; Lin, Wei-De; Liao, Wen-Ling; Tsai, Ya-Ching; Liao, Jiunn-Wang; Tsai, Fuu-Jen (Scientific reports, 2020)
Keywords: 5'-Nucleotidase - genetics; 631/208/176; 692/53/2423; Adult; Aged; Animals; Antigens, CD - genetics; Astrocytes; Beta cells; Case-Control Studies; Cerebral infarction; Deoxyribonucleic acid; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; DNA; DNA (Cytosine-5-)-Methyltransferase 1 - genetics; DNA Methylation; DNA methyltransferase; DNMT1 protein; Epigenesis, Genetic; Epigenetics; Female; Fucosyltransferases - genetics; Gene expression; Gene Expression Regulation; Gene silencing; Genetic diversity; Genome-wide association studies; Genomes; Glial fibrillary acidic protein; Humanities and Social Sciences; Humans; Insulin; Insulin - metabolism; Insulin secretion; Insulin-like growth factor I; Insulin-like growth factors; Insulin-Secreting Cells - metabolism; Ischemia; Male; Mice; Middle Aged; multidisciplinary; Neurogenesis; Neurological diseases; Nucleotidase; Pancreas; Polyethylene; Polyethylene glycol; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptor, Insulin - genetics; RNA, Messenger - blood; RNA, Messenger - genetics; Rodents; Science; Science (multidisciplinary); Serum levels; Signal Transduction; Single-nucleotide polymorphism; Stroke; Synaptophysin; Transfection