N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis

• Published in: Genes & diseases Vol. 10; no. 2; pp. 554 - 567
• Main Authors: Peng, Wan-Xin, Liu, Fei, Jiang, Jia-Hong, Yuan, Hang, Zhang, Ziqiang, Yang, Liu, Mo, Yin-Yuan
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2023; Chongqing Medical University; KeAi Communications Co., Ltd
• Subjects: Full Length; IGF2BP2; LINC00901; MYC; N6-methyladenosine modification (m6A); PDAC; YTHDF1; YTHDF1; PDAC; IGF2BP2; LINC00901; MYC; N6-methyladenosine modification (m6A)

Accumulating evidence indicates that RNA methylation at N6-methyladenosine (m6A) plays an important regulatory role in gene expression and aberrant mRNA m6A modification is often associated with a variety of cancers. However, little is known whether and how m6A-modification impacts long non-coding R...