Effect of Beta-Blocker Therapy on Rehospitalization Rates in Women Versus Men With Heart Failure and Preserved Ejection Fraction

• Published in: The American journal of cardiology Vol. 105; no. 2; pp. 229 - 234
• Main Authors: Farasat, S. Morteza, Bolger, Dennis T., Shetty, Veena, Menachery, Elizabeth P., Gerstenblith, Gary, Kasper, Edward K., Najjar, Samer S.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.01.2010; Elsevier; Elsevier Limited
• Subjects: Adrenergic beta-Antagonists - therapeutic use; Aged; Aged, 80 and over; Beta blockers; Biological and medical sciences; Cardiology; Cardiology. Vascular system; Cardiovascular; Cardiovascular system; Comparative analysis; Female; Follow-Up Studies; Heart; Heart failure; Heart Failure - complications; Heart Failure - physiopathology; Heart Failure - therapy; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Hospitalization; Humans; Investigative techniques of hemodynamics; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Men; Middle Aged; Patient Discharge; Patient Readmission - statistics & numerical data; Prospective Studies; Risk Factors; Sex Factors; Stroke Volume - physiology; Women; Human; Heart failure; Rate; Cardiovascular disease; Male; Treatment; Rehospitalization; Heart disease; Female; Circulatory system; Hemodynamics; Cardiology; Woman; Comparative study; Ejection fraction

Beta blockers are empirically used in many patients with heart failure (HF) and preserved ejection fraction (HFpEF) because they allow more time for diastolic filling and because they improve outcomes in patients with systolic HF. However, recent data suggest that impaired chronotropic and vasodilat...