Progression from Normal to Reduced Left Ventricular Ejection Fraction in Patients With Concentric Left Ventricular Hypertrophy After Long-Term Follow-Up

• Published in: The American journal of cardiology Vol. 108; no. 7; pp. 997 - 1001
• Main Authors: Krishnamoorthy, Arun, Brown, Timothy, Ayers, Colby R., Gupta, Sachin, Rame, J. Eduardo, Patel, Parag C., Markham, David W., Drazner, Mark H.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.10.2011; Elsevier; Elsevier Limited
• Subjects: Biological and medical sciences; Cardiology; Cardiology. Vascular system; Cardiovascular; Cardiovascular disease; Cardiovascular system; Disease Progression; Echocardiography; Female; Follow-Up Studies; Genotype & phenotype; Heart Ventricles - diagnostic imaging; Heart Ventricles - physiopathology; Humans; Hypertrophy, Left Ventricular - diagnostic imaging; Hypertrophy, Left Ventricular - physiopathology; Investigative techniques of hemodynamics; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Middle Aged; Prognosis; Retrospective Studies; Stroke Volume - physiology; Time Factors; Ventricular Function, Left - physiology; Human; Prognosis; Patient; Normal; Long term; Left ventricle; Follow up study; Evolution; Ventricular ejection; Circulatory system; Hemodynamics; Cardiology; Ejection fraction; Hypertrophy

Whether concentric left ventricular (LV) hypertrophy (LVH) is a common precursor to depressed LV ejection fraction (EF) in humans is uncertain. From 1992 through 1994, 555 patients at our institution underwent echocardiography and had LVH (posterior or septal wall thickness ≥1.3 cm or concentric LVH...