Overcoming Cancer Persister Cells by Stabilizing the ATF4 Promoter G‐quadruplex - Xiao, Chengmei; Li, Yipu; Liu, Yushuang; Dong, Ruifang; He, Xiaoyu; Lin, Qing; Zang, Xin; Wang, Kaibo; Xia, Yuanzheng; Kong, Lingyi (Advanced science, 2024)
Keywords: Activating Transcription Factor 4 - genetics; Activating Transcription Factor 4 - metabolism; Amino acids; ATF4; Brain cancer; Cancer therapies; Cell death; Cell Line, Tumor; Chemotherapy; Clinical trials; coptisine; Drug Resistance, Neoplasm - drug effects; Drug Resistance, Neoplasm - genetics; G-Quadruplexes; Genomes; Glutamine - genetics; Glutamine - metabolism; Glutamine - pharmacology; glutamine‐restrictive therapy; G‐quadruplex; Humans; Kinases; Lung cancer; Metabolism; Neoplasms - drug therapy; Neoplasms - genetics; Neoplasms - metabolism; NMR; Nuclear magnetic resonance; Physiology; Promoter Regions, Genetic - genetics; Proteins; Transcription factors; Tumors; G‐quadruplex; coptisine; ATF4; glutamine‐restrictive therapy