CTX-M β-Lactamase-Producing Escherichia coli in French Hospitals: Prevalence, Molecular Epidemiology, and Risk Factors

• Published in: Journal of Clinical Microbiology Vol. 45; no. 2; pp. 620 - 626
• Main Authors: Lavigne, Jean-Philippe, Marchandin, Hélène, Delmas, Julien, Moreau, Jérôme, Bouziges, Nicole, Lecaillon, Evelyne, Cavalie, Laurent, Jean-Pierre, Hélène, Bonnet, Richard, Sotto, Albert
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.02.2007
• Subjects: Aged; Bacteriology; beta-Lactamases; beta-Lactamases - biosynthesis; beta-Lactamases - genetics; Biological and medical sciences; Electrophoresis, Gel, Pulsed-Field; Epidemiology; Epidemiology, Molecular; Escherichia coli; Escherichia coli - classification; Escherichia coli - drug effects; Escherichia coli - enzymology; Escherichia coli - genetics; Escherichia coli Infections; Escherichia coli Infections - epidemiology; Escherichia coli Infections - microbiology; Female; France; France - epidemiology; Fundamental and applied biological sciences. Psychology; Hospitals; Human health and pathology; Humans; Infectious diseases; Life Sciences; Male; Medical sciences; Microbiology; Miscellaneous; Molecular Epidemiology; Phylogeny; Prevalence; Risk Factors; Urinary Tract Infections; Urinary Tract Infections - epidemiology; Urinary Tract Infections - microbiology; France; Prevalence; Microbiology; Enzyme; Escherichia coli; Risk factor; Molecular epidemiology; Bacteria; Hydrolases; Genotype; β-Lactamase; Enterobacteriaceae

In 2004, 65 CTX-M-producing Escherichia coli isolates were collected from infected patients in four French hospitals. The blaCTX₋M₋₁₅ genes were predominant. Pulsed-field gel electrophoresis highlighted a clonal propagation of CTX-M-15-producing strains belonging to phylogenetic group B2, notably in...