Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues - Chen, Michelle B.; Yang, Andrew C.; Yousef, Hanadie; Lee, Davis; Chen, Winnie; Schaum, Nicholas; Lehallier, Benoit; Quake, Stephen R.; Wyss-Coray, Tony (Cell reports (Cambridge), 2020)
Keywords: aging; Aging - blood; Aging - genetics; Aging - physiology; Animals; Arteries - physiology; Blood Circulation - physiology; blood-brain barrier; Brain - cytology; brain endothelial cells; Capillaries - physiology; Endothelial Cells - metabolism; Lipopolysaccharides - administration & dosage; Lipopolysaccharides - pharmacology; Male; Mice, Inbred C57BL; plasma proteome; rejuvenation; single-cell RNA sequencing; Transcription, Genetic - drug effects; Transcriptome - genetics; Veins - physiology; blood-brain barrier; single-cell RNA sequencing; brain endothelial cells; aging; rejuvenation; plasma proteome