Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome

• Published in: Molecular metabolism (Germany) Vol. 42; p. 101076
• Main Authors: Hartstra, Annick V., Schüppel, Valentina, Imangaliyev, Sultan, Schrantee, Anouk, Prodan, Andrei, Collard, Didier, Levin, Evgeni, Dallinga-Thie, Geesje, Ackermans, Mariette T., Winkelmeijer, Maaike, Havik, Stefan R., Metwaly, Amira, Lagkouvardos, Ilias, Nier, Anika, Bergheim, Ina, Heikenwalder, Mathias, Dunkel, Andreas, Nederveen, Aart J., Liebisch, Gerhard, Mancano, Giulia, Claus, Sandrine P., Benítez-Páez, Alfonso, la Fleur, Susanne E., Bergman, Jacques J., Gerdes, Victor, Sanz, Yolanda, Booij, Jan, Kemper, Elles, Groen, Albert K., Serlie, Mireille J., Haller, Dirk, Nieuwdorp, Max
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.12.2020; Elsevier
• Subjects: Gut-brain axis; Gutmicrobiota; Metabolites; Obesity; Original; Obesity; Metabolites; Gutmicrobiota; Gut-brain axis

Increasing evidence indicates that intestinal microbiota play a role in diverse metabolic processes via intestinal butyrate production. Human bariatric surgery data suggest that the gut-brain axis is also involved in this process, but the underlying mechanisms remain unknown. We compared the effect...