Euryhaline pufferfish NBCe1 differs from nonmarine species NBCe1 physiology

• Published in: American Journal of Physiology: Cell Physiology Vol. 302; no. 8; pp. C1083 - C1095
• Main Authors: Chang, Min-Hwang, Plata, Consuelo, Kurita, Yukihiro, Kato, Akira, Hirose, Shigehisa, Romero, Michael F
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 15.04.2012
• Subjects: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid - pharmacology; Amino Acid Substitution - drug effects; Animals; Bicarbonates - metabolism; Biological Transport - drug effects; Epithelial Cells - drug effects; Epithelial Cells - metabolism; Epithelial Cells - physiology; Female; Fish; Gene expression; Humans; Kidneys; Kinetics; Lithium - metabolism; Marine; Membrane Potentials - drug effects; Membrane Transporters, Ion Channels and Pumps; Nonnative species; Salt; Sodium - metabolism; Sodium-Bicarbonate Symporters - genetics; Sodium-Bicarbonate Symporters - metabolism; Takifugu - genetics; Takifugu - metabolism; Takifugu - physiology; Takifugu obscurus; Teleostei; Xenopus; Xenopus laevis

Marine fish drink seawater and eliminate excess salt by active salt transport across gill and gut epithelia. Euryhaline pufferfish (Takifugu obscurus, mefugu) forms a CaCO(3) precipitate on the luminal gut surface after transitioning to seawater. NBCe1 (Slc4a4) at the basolateral membrane of intesti...