Autoantibodies in Sjögren's syndrome and its classification criteria

• Published in: Journal of translational autoimmunity (Online) Vol. 5; p. 100138
• Main Authors: Veenbergen, Sharon, Kozmar, Ana, van Daele, Paul L.A., Schreurs, Marco W.J.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2022; Elsevier
• Subjects: Autoantibodies; Classification criteria; Sjögren's syndrome; Sjögren's syndrome; Classification criteria; Autoantibodies

Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by immune-mediated injury of exocrine glands. Extensive lymphocytic infiltrates may contribute to the destruction and loss of secretory function of glands. B-cell hyperactivity is a key feature of the disease resulting in th...