p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis - Olivero, Christiane E.; Martínez-Terroba, Elena; Zimmer, Joshua; Liao, Clara; Tesfaye, Ephrath; Hooshdaran, Nima; Schofield, Jeremy A.; Bendor, Jordan; Fang, Dorthy; Simon, Matthew D.; Zamudio, Jesse R.; Dimitrova, Nadya (Molecular cell, 2020)
Keywords: Animals; Carcinogenesis - genetics; Cell Line; Cell Proliferation; Cells, Cultured; Chromatin - metabolism; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; long noncoding RNA; lung cancer; Lung Neoplasms - genetics; Lung Neoplasms - pathology; Mice; Mice, Inbred C57BL; mouse model of cancer; MYC; p53; Promoter Regions, Genetic; Proto-Oncogene Proteins c-myc - antagonists & inhibitors; Proto-Oncogene Proteins c-myc - genetics; Proto-Oncogene Proteins c-myc - metabolism; Pvt1; RNA, Long Noncoding - antagonists & inhibitors; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; Stress, Physiological - genetics; tumor suppressor; Tumor Suppressor Protein p53 - genetics; Tumor Suppressor Protein p53 - metabolism; lung cancer; Pvt1; MYC; long noncoding RNA; tumor suppressor; mouse model of cancer; p53