Emerging SARS-CoV-2 variants: Why, how, and what's next?

• Published in: Cell insight Vol. 1; no. 3; p. 100029
• Main Authors: Chen, Yu, Liu, Qianyun, Zhou, Li, Zhou, You, Yan, Huan, Lan, Ke
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2022; Published by Elsevier B.V. on behalf of Wuhan University; Elsevier
• Subjects: Deltacron; Mutation rate; Mutations in the Spike; Omicron; Review; SARS-CoV-2 variants; SARS-CoV-2 variants; Mutation rate; Deltacron; Mutations in the Spike; Omicron

The emergence of the SARS-CoV-2 Omicron variant poses a striking threat to human society. More than 30 mutations in the Spike protein of the Omicron variant severely compromised the protective immunity elicited by either vaccination or prior infection. The persistent viral evolutionary trajectory ge...