Persisting symptoms in patients with Hashimoto’s disease despite normal thyroid hormone levels: Does thyroid autoimmunity play a role? A systematic review

• Published in: Journal of translational autoimmunity (Online) Vol. 4; p. 100101
• Main Authors: Groenewegen, Karelina L., Mooij, Christiaan F., van Trotsenburg, A.S. Paul
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2021; Elsevier
• Subjects: Hashimoto’s disease; Hypothyroidism; Persisting symptoms; Quality of life; Review article; Thyroid auto-immunity; Persisting symptoms; Thyroid auto-immunity; Hashimoto’s disease; Hypothyroidism; Quality of life

Patients with hypothyroidism due to Hashimoto’s disease (HD) may experience persisting symptoms despite normal serum thyroid hormone (TH) levels. Several hypotheses have been postulated to explain these persisting symptoms. We hypothesized that thyroid autoimmunity may play a role. A systematic lite...