Distinct Ezrin Truncations Differentiate Metastases in Sentinel Lymph Nodes from Unaffected Lymph Node Tissues, from Primary Breast Tumors, and from Healthy Glandular Breast Tissues

• Published in: Translational oncology Vol. 11; no. 1; pp. 1 - 10
• Main Authors: Röwer, Claudia, George, Christian, Reimer, Toralf, Stengel, Bernd, Radtke, Anngret, Gerber, Bernd, Glocker, Michael O.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2018; Neoplasia Press; Elsevier
• Subjects: Original article

BACKGROUND: Lymph node metastasis status is a prognostic factor for further lymph node involvement and for patient survival in breast cancer patients. Frozen section analysis of lymph nodes is a reliable method for detection of macro-metastases. However, this method is far less effective in detectin...