Bortezomib is a rapid mobilizer of hematopoietic stem cells in mice via modulation of the VCAM-1/VLA-4 axis

• Published in: Blood Vol. 124; no. 17; pp. 2752 - 2754
• Main Authors: Ghobadi, Armin, Rettig, Michael P., Cooper, Matthew L., Holt, Matthew S., Ritchey, Julie K., Eissenberg, Linda, DiPersio, John F.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 23.10.2014; American Society of Hematology
• Subjects: Animals; Boronic Acids - pharmacology; Bortezomib; Correspondence; Drug Synergism; Granulocyte Colony-Stimulating Factor - pharmacology; Hematopoietic Stem Cell Mobilization - methods; Hematopoietic Stem Cells - drug effects; Hematopoietic Stem Cells - metabolism; Heterocyclic Compounds - pharmacology; Integrin alpha4beta1 - genetics; Integrin alpha4beta1 - metabolism; Mice, Inbred BALB C; Mice, Knockout; Proteasome Inhibitors - pharmacology; Pyrazines - pharmacology; Time Factors; Vascular Cell Adhesion Molecule-1 - metabolism