Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer
Hsp70 is a stress-inducible molecular chaperone that is required for cancer development at several steps. Targeting the active site of Hsp70 has proven relatively challenging, driving interest in alternative approaches. Hsp70 collaborates with the Bcl2-associated athanogene 3 (Bag3) to promote cell...
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Published in | Molecular cancer therapeutics Vol. 14; no. 3; pp. 642 - 648 |
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Main Authors | , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.03.2015
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Subjects | |
Online Access | Get full text |
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