Allergen-induced increase of eosinophil cationic protein in nasal lavage fluid: Effect of the glucocorticoid budesonide

• Published in: Journal of allergy and clinical immunology Vol. 85; no. 5; pp. 891 - 895
• Main Authors: Bisgaard, Hans, Grønborg, Henrik, Mygind, Niels, Dahl, Ronald, Lindqvist, Nils, Venge, Per
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.05.1990; Elsevier
• Subjects: Adult; Biological and medical sciences; Blood Proteins - analysis; Budesonide; Clinical Trials as Topic; Double-Blind Method; Eosinophil Granule Proteins; Female; Humans; Immunopathology; Male; Medical sciences; Nasal Mucosa - metabolism; Pregnenediones - pharmacology; Pregnenediones - therapeutic use; Rhinitis, Allergic, Perennial - drug therapy; Ribonucleases; Therapeutic Irrigation; MBP; ECP; Human; Immunopathology; Allergy; Corticosteroid; Chemotherapy; Treatment; Immunological investigation; ENT disease; Exploration

It was our aim to study the effect of nasal allergen provocation on the concentration of eosinophil cationic protein (ECP) in nasal lavage fluid, with and without glucocorticoid pretreatment. Twenty grass-pollen sensitive volunteers were provoked outside the pollen season on 2 consecutive days after...