Cadmium delays puberty onset and testis growth in adolescents

• Published in: Clinical endocrinology (Oxford) Vol. 83; no. 3; pp. 357 - 362
• Main Authors: Interdonato, Monica, Pizzino, Gabriele, Bitto, Alessandra, Galfo, Federica, Irrera, Natasha, Mecchio, Anna, Pallio, Giovanni, Ramistella, Vincenzo, Luca, Filippo De, Santamaria, Angelo, Minutoli, Letteria, Marini, Herbert, Squadrito, Francesco, Altavilla, Domenica
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.09.2015; Wiley Subscription Services, Inc
• Subjects: Adolescent; Cadmium - urine; Child; Cross-Sectional Studies; Follicle Stimulating Hormone - blood; Humans; Inhibins - blood; Linear Models; Luteinizing Hormone - blood; Male; Organ Size - physiology; Puberty - blood; Puberty - physiology; Puberty - urine; Testis - growth & development; Testosterone - blood; Time Factors; Urban Health - statistics & numerical data; Urban Population - statistics & numerical data

Summary Objective Cadmium (Cd) has been shown to impair pubertal development in experimental animals. However, no data are available for male adolescents with increased urinary cadmium levels. Design The aim of this cross‐sectional study was to evaluate pubertal onset and pituitary–gonadal axis horm...