Treatment with astragaloside IV reduced blood glucose, regulated blood lipids, and protected liver function in diabetic rats

• Published in: Journal of international medical research Vol. 49; no. 3; p. 300060519841165
• Main Author: Han, Dong
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.03.2021; Sage Publications Ltd; SAGE Publishing
• Subjects: Animals; Antioxidants - metabolism; Blood Glucose - metabolism; Diabetes; Diabetes Mellitus, Experimental - drug therapy; Glucose; Lipids; Liver; Liver - metabolism; Oxidative Stress; Pre-Clinical Research Report; Rats; Rodents; Saponins; Triterpenes; blood glucose; rat model; liver function protection; diabetes mellitus; Astragaloside IV; blood lipids; oxidative stress

Objectives To investigate the effects of astragaloside IV on blood glucose, blood lipids, and liver function in diabetic rats. Methods Fifty diabetic rats were randomly placed into five groups (n = 10 each): the diabetes mellitus (DM) group received intragastric saline, the metformin hydrochloride g...