Analysis of lncRNA-Mediated ceRNA Crosstalk and Identification of Prognostic Signature in Head and Neck Squamous Cell Carcinoma

• Published in: Frontiers in pharmacology Vol. 10; p. 150
• Main Authors: Pan, Yunbao, Liu, Guohong, Wang, Dujuan, Li, Yirong
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 04.03.2019
• Subjects: ceRNA network; head and neck squamous cell carcinoma; long non-coding RNAs; microRNA; Pharmacology; TCGA; microRNA; ceRNA network; long non-coding RNAs; TCGA; head and neck squamous cell carcinoma

Long non-coding RNA (lncRNA) can act as ceRNA to regulate the expression of target genes by sponging miRNAs, and therefore plays an essential role in tumor initiation and progression. However, functional roles and regulatory mechanisms of lncRNAs as ceRNAs in head and neck squamous cell carcinoma (H...