Identification and Functional Verification of MicroRNA-16 Family Targeting Intestinal Divalent Metal Transporter 1 (DMT1) in vitro and in vivo

• Published in: Frontiers in physiology Vol. 10; p. 819
• Main Authors: Jiang, Shuxia, Guo, Shihui, Li, Huifang, Ni, Yingdong, Ma, Wenqiang, Zhao, Ruqian
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 27.06.2019
• Subjects: DMT1; functional verification; intestine; microRNA-16 family; Physiology; regulation; functional verification; intestine; regulation; DMT1; microRNA-16 family

Divalent metal transporter 1 (DMT1) is a key transporter of iron uptake and delivering in human and animals. However, post-transcriptional regulation of DMT1 is poorly understood. In this study, bioinformatic algorithms (TargetScan, PITA, miRanda, and miRDB) were applied to predict, screen, analyze,...