Hepatocellular Senescence: Immunosurveillance and Future Senescence-Induced Therapy in Hepatocellular Carcinoma

• Published in: Frontiers in oncology Vol. 10; p. 589908
• Main Authors: Liu, Peng, Tang, Qinghe, Chen, Miaomiao, Chen, Wenjian, Lu, Yanli, Liu, Zhongmin, He, Zhiying
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 27.11.2020
• Subjects: cellular senescence; hepatocellular carcinoma; hepatocellular senescence; immunosurveillance; Oncology; senescence-associated secretory phenotype; senescence-induced therapy; hepatocellular senescence; senescence-induced therapy; cellular senescence; senescence-associated secretory phenotype; immunosurveillance; hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. The lack of effective targeted drugs has become a challenge on treating HCC patients. Cellular senescence is closely linked to the occurrence, development, and therapy of tumor. Induction of cellular senesc...