Synthesis of rearranged indole diterpenes of the paxilline type

• Published in: Natural product reports Vol. 39; no. 5; pp. 946 - 968
• Main Authors: Schatz, Devon J, Kuenstner, Eric J, George, David T, Pronin, Sergey V
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 26.05.2022
• Subjects: Biological effects; Biological Products - chemistry; biosynthesis; Chemists; Congeners; Crystallography; Diterpenes; Diterpenes - chemistry; diterpenoids; fungi; Indoles - chemistry; Metabolites; Natural products; paxilline; Synthesis

Covering: up to 2021 Rearranged indole diterpenes of the paxilline type comprise a large group of fungal metabolites that possess diverse structural features and potentially useful biological effects. The unique indoloterpenoid motif, which is common to all congeners, was first confirmed by crystall...