Sambamba: fast processing of NGS alignment formats

• Published in: Bioinformatics (Oxford, England) Vol. 31; no. 12; pp. 2032 - 2034
• Main Authors: Tarasov, Artem, Vilella, Albert J., Cuppen, Edwin, Nijman, Isaac J., Prins, Pjotr
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 15.06.2015
• Subjects: Algorithms; Applications Notes; EPS-2; Genomics; High-Throughput Nucleotide Sequencing - methods; Humans; Laboratorium voor Nematologie; Laboratory of Nematology; Sequence Alignment; Sequence Analysis, DNA - methods; Software

Sambamba is a high-performance robust tool and library for working with SAM, BAM and CRAM sequence alignment files; the most common file formats for aligned next generation sequencing data. Sambamba is a faster alternative to samtools that exploits multi-core processing and dramatically reduces proc...