Clinical features and prognostic factors in patients with bone metastases from non-small cell lung cancer

• Published in: Journal of international medical research Vol. 48; no. 5; p. 300060520925644
• Main Authors: Wu, Xiao-Tian, Zhou, Jian-Wei, Pan, Long-Ci, Ge, Ting
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.05.2020; Sage Publications Ltd; SAGE Publishing
• Subjects: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase - blood; Bone Density Conservation Agents - therapeutic use; Bone Neoplasms - diagnosis; Bone Neoplasms - mortality; Bone Neoplasms - secondary; Bone Neoplasms - therapy; Calcium - blood; Carcinoma, Non-Small-Cell Lung - diagnosis; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - secondary; Carcinoma, Non-Small-Cell Lung - therapy; Chemoradiotherapy, Adjuvant - statistics & numerical data; Dehydrogenases; Diphosphonates - therapeutic use; Female; Humans; Kaplan-Meier Estimate; L-Lactate Dehydrogenase - blood; Lung cancer; Lung Neoplasms - blood; Lung Neoplasms - mortality; Lung Neoplasms - pathology; Lung Neoplasms - therapy; Male; Medical prognosis; Mentoring programs; Metastasis; Middle Aged; Multivariate analysis; Phosphatase; Pneumonectomy - statistics & numerical data; Prognosis; Retrospective Clinical Research Report; Retrospective Studies; Risk Factors; Severity of Illness Index; Survival Rate; Young Adult; non-small cell lung cancer; lactate dehydrogenase; Bone metastasis; alkaline phosphatase; prognostic factor; Eastern Cooperative Oncology Group performance status

Objective To investigate the clinical features and evaluate the prognostic factors in patients with bone metastases from non-small cell lung cancer (NSCLC). Methods We retrospectively investigated 356 patients with NSCLC with bone metastases from January 2012 to December 2017. The overall survival (...