Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn’s Disease Patients

• Published in: Journal of Crohn's and colitis Vol. 10; no. 3; pp. 296 - 305
• Main Authors: Liguori, Giuseppina, Lamas, Bruno, Richard, Mathias L., Brandi, Giovanni, da Costa, Gregory, Hoffmann, Thomas W., Di Simone, Massimo Pierluigi, Calabrese, Carlo, Poggioli, Gilberto, Langella, Philippe, Campieri, Massimo, Sokol, Harry
• Format: Journal Article
• Language: English
• Published: UK Oxford University Press 01.03.2016; Elsevier - Oxford University Press
• Subjects: Adult; Biodiversity; Case-Control Studies; Colon - microbiology; Crohn Disease - microbiology; Disease Progression; DNA, Fungal - analysis; DNA, Fungal - isolation & purification; Dysbiosis - diagnosis; Dysbiosis - microbiology; Female; Fungi - genetics; Fungi - isolation & purification; Gastrointestinal Microbiome; Human health and pathology; Humans; Intestinal Mucosa - microbiology; Life Sciences; Male; Middle Aged; Original; Prospective Studies; Real-Time Polymerase Chain Reaction; Inflammatory bowel disease; fungal microbiota; mucosa-associated microbiota

Background and Aims: Gut microbiota is involved in many physiological functions and its imbalance is associated with several diseases, particularly with inflammatory bowel diseases. Mucosa-associated microbiota could have a key role in induction of host immunity and in inflammatory process. Although...