Induction of Intestinal Th17 Cells by Flagellins From Segmented Filamentous Bacteria

• Published in: Frontiers in immunology Vol. 10; p. 2750
• Main Authors: Wang, Yanling, Yin, Yeshi, Chen, Xin, Zhao, Yongjia, Wu, Yichen, Li, Yifei, Wang, Xin, Chen, Huahai, Xiang, Charlie
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 22.11.2019
• Subjects: flagellin; IL-17A; Immunology; segmented filamentous bacteria; SI EC; Th17 cells; segmented filamentous bacteria; flagellin; SI EC; IL-17A; Th17 cells

T-helper-17 (Th17) cells are a subset of CD4+ T cells that can produce the cytokine interleukin (IL)-17 and play vital roles in protecting the host from bacterial and fungal infections, especially at the mucosal surface. These are abundant in the small intestinal lamina propria (SILP) and their diff...